Acta diabetologia latina

, Volume 12, Issue 2, pp 150–159

Modifications of pancreatic islet tissue after internal biliary fistula (experimental research)

  • Massimo Ermini
  • Massimo Seccia
  • Giuseppe Evangelista
Article

Summary

The morphometric study of the endocrine pancreas carried out in normal dogs and in dogs with a total internal biliary fistula (cholecystojejunostomy after closure of the common bile-duct) has shown that, following this operation, obvious and statistically significant changes take place which indicate a considerable increase of the insular mass. This anatomic modification, probably induced by the suppression of bile flow into the duodenum, is the result both of hypertrophy and hyperplasia of the endocrine pancreatic apparatus and seems to go hand in hand with an increase in insulinopoietic activity.

Key-words

Biliary fistula Endocrine pancreas Experimental biliary fistula Internal biliary fistula Pancreatic islet tissue 

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Copyright information

© The Publishing House «IL PONTE» 1975

Authors and Affiliations

  • Massimo Ermini
    • 1
  • Massimo Seccia
    • 1
  • Giuseppe Evangelista
    • 1
  1. 1.Istituto Di Patologia Speciale Chirurgica E PropedeuticaClinica I Dell’Università di PisaItaly

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