Long-term human breast carcinoma cell lines of metastatic origin: Preliminary characterization
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Nineteen human breast carcinoma cell lines have been established as continous cultures during the past 6 years in our laboratory. This preliminary report is designed to list the lines by their designated code numbers (MDA-MB) and present a brief summary of their morphological, cytogenetic and biochemical characteristics. Sixteen of our lines were obtained from pleural effusions, two from brain metastases, and one from pericardial fluid. All lines have been shown to be distinct entities and are uncontaminated by HeLa cells or each other. A lq marker chromosome is present in all but one of the lines examined.
Key wordscell lines metastatic human breast carcinoma
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- 10.Pathak, S., M. J. Siciliano, R. Cailleau, C. L. Wiseman, and T. C. Hsu. A human breast adenocarcinoma with chromosome and isozyme markers similar to those of the HeLa line. J. Nat. Cancer Inst., in press.Google Scholar
- 11.Cailleau, R., B. Mackay, r. K. Young, and W. J. Reeves, Jr. 1974. Tissue culture studies on pleural effusions from breast carcinoma patients. Can. Res. 34: 801–809.Google Scholar
- 13.Cruciger, Q., S. Pathak, P. Barker, R. Cailleau, N. Eckles, and G. Blumenschein. 1978. Consistent translocation of lq chromosome in metastatic breast cancer tissue and cell lines. Clinical correlations (abstr.). Clin. Res. 26: 433.Google Scholar
- 14.Hokanson, K. M. S. 1978. Human breast tumor cell lines and their use of steroid hormones. Doctoral dissertation. University of Texas Health Science Center, Graduate School of Biomedical Sciences.Google Scholar