Calcified Tissue International

, Volume 49, Issue 2, pp 101–106

Bone mineral density of the spine in normal Japanese subjects using dual-energy X-ray absorptiometry: Effect of obesity and menopausal status

  • Kokai Kin
  • Kazuhiro Kushida
  • Kaoru Yamazaki
  • Shozo Okamoto
  • Tetsuo Inoue
Clinical Investigations


Bone mineral density (BMD) of the lumbar spine was measured to determine normal Japanese values and to examine the effect of obesity and menopausal status on BMD. Normal Japanese subjects (N=1,296, 1,048 women and 248 men) were examined using dual-energy X-ray absorptiometry. BMD for men peaked between age 20 and 29. For women, there was abrupt bone loss after age 50. Obese women within the same age bracket had a higher BMD than thin women after age 40–49. We determined that BMD began to decline during the irregular menstruation period before the onset of menopause. We conclude that there is a positive correlation between obesity and BMD, particularly in postmenopausal women. In addition, we found that bone loss related to menopause begins during the irregular menstruation period before menopause.

Key words

Bone mineral density Menopause Body mass index Dual-energy X-ray absorptiometry Lumbar spine 


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Copyright information

© Springer-Verlag New York Inc 1991

Authors and Affiliations

  • Kokai Kin
    • 1
  • Kazuhiro Kushida
    • 1
  • Kaoru Yamazaki
    • 1
  • Shozo Okamoto
    • 1
  • Tetsuo Inoue
    • 1
  1. 1.Department of Orthopedic SurgeryHamamatsu University School of MedicineHamamatsuJapan

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