Lipids

, Volume 34, Supplement 1, pp S303–S305 | Cite as

n-3 fatty acids and coronary heart disease—the urgent need of clinical trials

Clinical Trials And New Products

Conclusions

Data from epidemiological studies, animal experiments, and clinical trials of biochemical effects in humans lend support for a beneficial role of n-3 PUFA in CHD. So far only a few trials of n-3 PUFA with clinical endpoints have been published. Further clinical studies in patients with acute myocardial ischemia, post-MI patients, patients undergoing coronary bypass surgery or stenting during PTCA, and patients with arrhythmias should be undertaken. Only results from controlled clinical trials with hard end points can establish whether n-3 PUFA reduce the risk of CHD and will have an impact on patient treatment.

Abbreviations

CHD

coronary heart disease

MI

myocardial infarction

PTCA

percutaneous transluminal coronary angioplasty

n-3 PUFA

n-3 polyunsaturated fatty acid

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Copyright information

© AOCS Press 1999

Authors and Affiliations

  1. 1.Department of MedicineHjørring/Brønderslev HospitalDenmark
  2. 2.Medi-Lab a.s.Copenhagen KDenmark

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