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Calcified Tissue International

, Volume 41, Issue 6, pp 351–352 | Cite as

Calcium absorption from a new calcium delivery system (CCM)

  • Kenneth T. Smith
  • Robert P. Heaney
  • Lawrence Flora
  • Sharilyn M. Hinders
Rapid Communication

Abstract

Absorption of calcium from a highly soluble form of calcium, a mixed calcium citrate-malate* salt (CCM), was tested against calcium carbonate and milk in both rats and humans. The rat method estimated absorption from the 6-day retention of an oral tracer, and the human method employed the standard double-isotope procedure. CCM was given both as a dry powder and in an organe juice beverage. In two experiments in rats calcium from CCM was absorbed at least as well as, if not better than from calcium carbonate or milk. In two separate experiments in humans, calcium from CCM was absorbed significantly better than from calcium carbonate or milk. We conclude that CCM exhibits excellent bioavailability and that this formulation is a useful addition to the forms of calcium now available either for direct supplementation or for food fortification.

Key words

Calcium absorption calcium carbonate citric acid malic acid 

References

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Copyright information

© Springer-Verlag New York Inc 1987

Authors and Affiliations

  • Kenneth T. Smith
    • 1
  • Robert P. Heaney
    • 2
  • Lawrence Flora
    • 1
  • Sharilyn M. Hinders
    • 2
  1. 1.Miami Valley LaboratoriesThe Procter & Gamble CompanyCincinnati
  2. 2.Creighton UniversityOmaha

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