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Diseases of the Colon & Rectum

, Volume 27, Issue 5, pp 325–330 | Cite as

Intraepithelial carcinoma of the anus in homosexual men

  • Thomas Croxson
  • Ada B. Chabon
  • Edwarda Rorat
  • Ira M. Barash
Article

Abstract

Anal warts (condylomata acuminata) from seven homosexual men revealed intraepithelial carcinoma (carcinomain situ) within the condylomatous tissue or in adjacent anal mucosa. All lesions displayed morphologic evidence of papillomavirus infection and two of the seven revealed histologic changes characteristic of herpes simplex infection. This association of viral infection with malignant transformation indicates that persistent or recurrent anal warts should be excised and thoroughly examined by histologic techniques. Since four of the seven patients had histories suspicious for or diagnostic of the acquired immunodeficiency syndrome (AIDS), we further suggest that homosexual men with persistent or recurrent perianal lesons be evaluated for the presence of the syndrome.

Key words

Anal carcinomain situ Condylomata acuminata Human papillomavirus Herpes simplex virus AIDS 

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Copyright information

© American Society of Colon and Rectal Surgeons 1984

Authors and Affiliations

  • Thomas Croxson
    • 1
    • 3
  • Ada B. Chabon
    • 1
    • 3
  • Edwarda Rorat
    • 1
    • 3
  • Ira M. Barash
    • 2
    • 3
  1. 1.Department of PathologyBeth Israel Medical CenterNew York
  2. 2.Department of SurgeryBeth Israel Medical CenterNew York
  3. 3.Mount Sinai School of Medicine of the City University of New YorkNew York

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