Calcified Tissue International

, Volume 43, Issue 2, pp 122–124 | Cite as

The effects of chronic dietary calcium supplementation on bone mineral density in ovariectomized Beagles

  • M. -S. Shih
  • J. Dixon
  • C. Anderson
Rapid Communications
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Revised:

Summary

Oral calcium tablets were given daily for 180 days to ovariectomized Beagle dams (n=4). Total serum calcium, and bone mineral content of midshaft femur were measured and compared to that of the controls (ovariectomized alone, n=4). The bone mineral density was significantly higher in the calcium supplemented dogs (p<0.01).

Key words

Ovariectomized Beagles Bone mineral content Calcium supplement Femur 
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References

  1. 1.
    Draper HH, Sapthes CA (1981) Calcium, phosphorus, and osteoporosis. Fed Proc 40:2434.PubMedGoogle Scholar
  2. 2.
    Urist MR (1976) Biochemistry of calcification. In: Bourne GH (ed) The Biochemistry and Physiology of Bone. 2nd ed, Vol IV, Academic Press, New York, pp 2–59.Google Scholar
  3. 3.
    Heaney RP (1981) Paradox of irreversibility of age-related bone loss. In: Menczel J, Robin GC, Makin M, Steinberg R (eds) Osteoporosis. John Wiley & Sons Ltd. New York. pp 15–20.Google Scholar
  4. 4.
    Brown EM (1980) Set-point for calcium: its role in normal and abnormal parathyroid secretion. In: Cohn DV, Talmage RV, Matthews JL (eds) Hormonal Control of Calcium Metabolism. Excerpta Medica, Amsterdam. pp 35–43.Google Scholar
  5. 5.
    Cooper CW, Peng T-C, Toverud SU, VanderWiel CJ, Talmage RV (1980) Calcitonin and feeding. In: Cohn DV, Talmage RV, Matthews, JL (eds) Hormonal Control of Calcium Metabolism. Excerpta Medical, Amsterdam, pp 271–274.Google Scholar
  6. 6.
    Gordan GS, Vaughan C (1976) Clinical Management of the Osteoporosis. HM & M Publishers Ltd., England.Google Scholar
  7. 7.
    Heaney RP, Recker RR (1980) Osteoporosis-related nutritional influences on bone: Calcium. In: DeLuca HF, Frost HM, Jee WSS, Johnston CC, Jr., Parfitt AM (eds) Osteoporosis: Recent Advances in Pathogenesis and Treatment. University Park Press, Baltimore, MD. pp 253–256.Google Scholar
  8. 8.
    Andersen AC (1970) The Beagle As An Experimental Dog. The Iowa State University Press, Ames, Iowa.Google Scholar
  9. 9.
    Jorch UM, Anderson C, Delaquerriere-Richardson LFO, Cook M (1982) Measurements of bone mineral content by photon absorptiometry of the Beagle. Am J Vet Res 43:907–908.PubMedGoogle Scholar
  10. 10.
    Delaquerriere-Richardson LFO, Anderson C, Jorch UM, Cook M (1982) Radiographic studies on bone in Beagles subjected to low levels of dietary lead since birth. Vet & Human Toxicol 24: 401–405.Google Scholar
  11. 11.
    Ettinger B, Genant HK, Cann CE (1987) Postmenopausal bone loss is prevented by treatment with low-dosage estrogen with calcium. Ann Intern Med 106: 40–45.PubMedGoogle Scholar
  12. 12.
    Martin RB, Butcher RL, Sherwood LL, Buchendahl P, Boyd RD, Farris D, Sharkey N, Dannucci G (1987) Effects of ovariectomy in Beagle dogs. Bone 8: 23–31.PubMedCrossRefGoogle Scholar
  13. 13.
    Consensus Conference: Osteoporosis. (1984) JAMA 252:799–802.Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • M. -S. Shih
    • 1
  • J. Dixon
    • 1
  • C. Anderson
    • 1
  1. 1.Department of Pathology, Health Sciences CentreThe University of Western OntarioLondonCanada

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