Calcified Tissue International

, Volume 44, Issue 4, pp 235–242 | Cite as

Predicting fractures in women by using forearm bone densitometry

  • Per Gärdsell
  • Olof Johnell
  • Bo E. Nilsson
Clinical Investigations


In 1,076 women the forearm bone mineral content (BMC) had been measured with single photon gamma absorptiometry (SPA) 10–16 years ago. The incidence of fractures incurred in the ensuing years (1975–1985) was recorded. The BMC had been significantly less in those women who were to have the types of fractures that are related to bone fragility but only in women measured during the first post-menopausal decades. From age 50–69, diminished BMC at the distal forearm site was associated with a threefold increase of relative risk whereas at the proximal site there was about a sixfold increase in relative risk. This association was not evident in the pppulation over 70 years of age because of a high frequency of fractures (mostly of the spine) in subjects with relatively high BMC values. Body weight and grip strength were significantly lower in the fracture group over 70 years of age

Key words

Bone mineral Fractures Body weight Strength Menopause 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Nilsson BE, Westlin NE (1977) Bone mineral content and fragility fractures. Clin Orthop 125:196–199PubMedGoogle Scholar
  2. 2.
    Finn Jensen G, Christiansen C, Boesen J, Hegedüs V, Transböl I (1983) Relationship between bone mineral content and frequency of postmenopausal fractures. Acta Med Scand 213:61–63CrossRefGoogle Scholar
  3. 3.
    Wasnich RD, Ross PD, Heibrun LK, Vogel JM (1985) Prediction of postmenopausal fracture risk with use of bone mineral measurements. Am J Obstet Gynecol 153:745–751PubMedGoogle Scholar
  4. 4.
    Melton LJ, Wahner HW, Richelson LS, O'Fallon WM, Riggs BL (1986) Osteoporosis and the risk of hip fracture. A J Epidemol 124:254–261Google Scholar
  5. 5.
    Nordin BEC, Polley K (1987) Metabolic consequences of the menopause. A cross-sectional, longitudinal, and intervention study on 557 normal postmenopausal women. Calcif Tissue Int (Suppl 1, Vol 41)Google Scholar
  6. 6.
    Wasnich RD, Ross PD, Heilbrun LK, Vogel JM (1987) Selection of the optimal skeletal site for fracture risk prediction. Clin Orthop 216:262–269PubMedGoogle Scholar
  7. 7.
    Ross PD, Wasnich RD, Heilbrun LK, Vogel JM (1987) Definition of a spine fracture threshold based upon prospective fracture risk. Bone 8:271–278PubMedCrossRefGoogle Scholar
  8. 8.
    Ross PD, Wasnich RD, Vogel JM (1988) Detection of prefracture spinal osteoporosis using bone mineral absorptiometry. J Bone Min Res 3:1–11Google Scholar
  9. 9.
    Melton LJ III, Wahner HW, Riggs BL (1988) Bone density measurement (Editorial). J Bone Min Res 3:ix-xCrossRefGoogle Scholar
  10. 10.
    Naclér LOW, Nilsson BE, Westlin NE (1974) An apparatur for gamma absorptiometry of bone—technical data. Opuscula Medicotechnica 12Google Scholar
  11. 11.
    Johnell O, Nilsson BE (1985) Hip fracture and accident disposition. Acta Orthop Scand 56:302–304PubMedCrossRefGoogle Scholar
  12. 12.
    Aniansson A, Zetterberg C, Hedberg M, Henriksson KG (1984) Impaired muscle function with aging. Clin Orthop 191:193–201PubMedGoogle Scholar
  13. 13.
    Johnell O, Sernbo I (1986) Health and social status in patients with hip fractures and controls. Age and Ageing 15:285–291PubMedCrossRefGoogle Scholar
  14. 14.
    Lindsay R, Dempster DW, Clemens T, Herrington BS, Wilt S (1984) Incidence, cost, and risk factors of fracture of the proximal femur in the U.S.A. Osteoporosis. Proc Copenhagen Int Symp on Osteoporosis, June 3–8, 311–315Google Scholar
  15. 15.
    Juel Riis B, Rödbro P, Christiansen C (1986) The role of serum concentrations of sex steroids and bone turnover in the development and occurrence of postmenopausal osteoporosis. Calcif Tissue Int 38:318–322CrossRefGoogle Scholar
  16. 16.
    Riggs BL, Melton LJ, Wahner HW (1983) Heterogeneity of involutional osteoporosis: evidence for two distinct osteoporosis syndrome. In: Frame B, Potts JT Jr (eds) Clinical Disorders of bone and mineral metabolism. Exerpta Medica, Amsterdam 337–342Google Scholar
  17. 17.
    Christiansen C, Gotfredsen A, Nillas L, Riis BJ, Thomsen K (1986) Spontaneous and oestrogen-caused bone changes in early postmenopausal women: a local or generalized phenomenon? XIX Eur Symp on Calcif Tissues, Stockholm, Sweden, June 15–19Google Scholar
  18. 18.
    Aloia JF, Vaswani A, Ellis K, Yuen K, Cohn SH (1985) A model for involutional bone loss. J Lab Clin Med 106:630–637PubMedGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • Per Gärdsell
    • 1
  • Olof Johnell
    • 1
  • Bo E. Nilsson
    • 1
  1. 1.Department of Orthopaedics, Malmö General HospitalLund UniversityMalmöSweden

Personalised recommendations