Calcified Tissue International

, Volume 39, Issue 2, pp 63–68

Nonmineralized and mineralized bone collagen in bone of immobilized monkeys

  • Gerald L. Mechanic
  • Donald R. Young
  • Albert J. Banes
  • Mitsuo Yamauchi
Laboratory Investigations

Summary

Monkey bones from different time periods of immobilization and reambulation of the monkeys were assessed histologically. The bone was also assessed biochemically for nonmineralized collagen in bone. Results indicate that more non-mineralized bone is present in monkeys that have been immobilized, and upon reambulation, these values tend to be normalized to control bone.

Key words

Bone Collagen Osteoporosis 

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Copyright information

© Springer-Verlag New York Inc. 1986

Authors and Affiliations

  • Gerald L. Mechanic
    • 1
    • 3
  • Donald R. Young
    • 2
  • Albert J. Banes
    • 1
    • 3
  • Mitsuo Yamauchi
    • 1
    • 3
  1. 1.Dental Research Center, Department of Biochemistry and NutritionUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Biomedical Research Division, Ames Research CenterNASAMoffett FieldUSA
  3. 3.Department of SurgeryUniversity of North Carolina at Chapel HillChapel HillUSA

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