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International Urology and Nephrology

, Volume 28, Issue 5, pp 607–613 | Cite as

Childhood renal diseases in Saudi Arabia. A clinicopathological study of 167 cases

  • S. A. Al-Rasheed
  • M. M. Al-Mugeiren
  • A. A. Al-Salloum
  • M. O. Al-Sohaibani
Article

Abstract

Between April 1982 and September 1994, 167 renal biopsies were performed in 167 children at King Khalid University Hospital, Riyadh, Saudi Arabia. The data were analysed to show a correlation between clinical presentation and histological findings. Nephrotic syndrome was the most common indication for renal biopsy, accounting for 77% of all cases. Of these, 23.3% showed minimal change lesions, 24% showed mesangial proliferative glomerulonephritis and 24% showed focal segmental glomerulosclerosis. We noted a higher incidence of congenital nephrotic syndrome and Alport's syndrome as compared with the West. On the other hand, IgA nephropathy was less common (3%), and there was a complete absence of type II membranoproliferative glomerulonephritis.

Keywords

Nephrotic Syndrome Lupus Nephritis Saudi Arabia International Urology Focal Segmental Glomerulosclerosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Abdulrahman, M. B., Elldrissy, A. T. H.: Childhood renal disorders in Saudi Arabia.Pediatr. Nephrol., 2, 368 (1988).CrossRefGoogle Scholar
  2. 2.
    Akhtar, M., Quinibi, W., Taher, S., Ginn, E., Furayh, O., Sanjad, S., Al-Sabban, E.: Spectrum of renal disease in Saudi Arabia.Ann. Saudi Med., 10, 37 (1990).Google Scholar
  3. 3.
    Mattoo, T. K., Mahmood, M. A., Al-Harbi, M.: Nephrotic syndrome in Saudi children. Clinicopathological study of 150 cases.Pediatr. Nephrol., 4, 517 (1990).PubMedCrossRefGoogle Scholar
  4. 4.
    Abdulrahman, M. B., Elldrissy, A. T. H., Shipkey, F. H., Al-Rasheed, S., Al-Mugeiren, M.: Clinicopathological features of childhood nephrotic syndrome in Saudi Arabia.Ann. Trop. Paediatr., 10, 125 (1990).Google Scholar
  5. 5.
    Al-Rasheed, S. A., Al-Mugeiren, M. M., Abdulrahman, M. B., Elldrissy, A. T. H.: The outcome of percutaneous renal biopsy in children: An analysis of 120 consecutive cases.Paediatr. Nephrol., 4, 600 (1990).CrossRefGoogle Scholar
  6. 6.
    Abdulrahman, M. B., Elldrissy, A. T. H., Hafeez, M. A., Wright, E. A., Omar, S. A.: Renal biopsy in Saudi children with nephrotic syndrome not responsive to corticosteroids: A preliminary report.Trop. Geog. Med., 38, 141 (1986).Google Scholar
  7. 7.
    Churg, J., Sobin, L. H.: Renal Disease Classification and Atlas of Glomerular Diseases. Igaku-Sobin, Tokyo 1982, pp. 3–18.Google Scholar
  8. 8.
    Bodaghi, E., Vazirian, Sh., Abtahi, M., Honarmand, M. T., Madani, A., Zia Shamsa, A. M.: Glomerular disease in children. “The Iranian experience”.Pediatr. Nephrol., 3, 213 (1989).PubMedCrossRefGoogle Scholar
  9. 9.
    Churg, J., Habib, R., White, R. H. R.: Pathology of the nephrotic syndrome in children.Lancet, 1, 1299 (1970).CrossRefGoogle Scholar
  10. 10.
    International Study of Kidney Diseases in Childhood: The nephrotic syndrome in children: Prediction of histopathology from clinical and laboratory characteristics at the time of diagnosis.Kidney Int., 13, 159 (1978).Google Scholar
  11. 11.
    Srivastava, R. N., Mayekar, G., Anand, R., Choudry, V. P., Ghai, O. P., Tandon, H. M.: Nephrotic syndrome in Indian children.Arch. Dis. Child., 50, 626 (1975).PubMedCrossRefGoogle Scholar
  12. 12.
    Seggie, J., Davies, P. G., Ninin, D., Henry, J.: Pattern of glomerulonephritis in Zimbabwe: Survey of disease characterized by nephrotic proteinuria.Q. J. Med., 209, 109 (1984).Google Scholar
  13. 13.
    Musa, A. M., Abu-Asha, H., Veress, B.: Nephrotic syndrome in Sudanese patients with Schistosomiasis mansoni infection.Ann. Trop. Med. Parasitol., 74, 615 (1980).PubMedGoogle Scholar
  14. 14.
    Report of the International Study of Kidney Diseases in Childhood: Prospective, controlled trial of cyclophosphamide therapy in children with nephrotic syndrome.Lancet, II, 423 (1974).Google Scholar
  15. 15.
    Editorial. Management and Diagnosis of Children with Nephrotic Syndrome.BMJ, 2, 1103 (1977).Google Scholar
  16. 16.
    McEnery, P. T., Couthinho, M.: Membranoproliferative glomerulonephritis. In: Holliday, M., Barratt, T. M., Avner, E. D. (eds): Pediatric Nephrology, Williams and Wilkins, Baltimore 1994, pp. 739–753.Google Scholar
  17. 17.
    Ko Kw, Ha Is, Jin, D. K., Cheong, H. I., Choi, Y., Kim, Yi, Lee, H. S.: Childhood renal disease in Korea.Pediatr. Nephrol., 1, 664 (1987).PubMedCrossRefGoogle Scholar
  18. 18.
    Ramia, S., Hossain, A., Bakir, T. M. F., Waller, D. K., Vivian, P. A.: Prevalence and subtypes of hepatitis B surface antigen (HBsAg) in Saudi population.Trop. Geog. Med., 38, 63 (1986).Google Scholar
  19. 19.
    Patel, P. J., Al-Rasheed, S. A., Al-Mugeiren, M. M., Malabarey, T.: Sonographic findings in infantile idiopathic nephrotic syndrome.Child. Nephrol. Urol., 11, 209 (1991).PubMedGoogle Scholar
  20. 20.
    Mattoo, T. K., Al-Sowailem, A.: Spectrum of renal pathology in 100 selected children with nephrotic syndrome.Ann. Saudi Med., 13, 420 (1993).PubMedGoogle Scholar

Copyright information

© Akadémiai Kiadó 1996

Authors and Affiliations

  • S. A. Al-Rasheed
    • 1
  • M. M. Al-Mugeiren
    • 1
  • A. A. Al-Salloum
    • 1
  • M. O. Al-Sohaibani
    • 2
  1. 1.Department of PaediatricsKing Khalid University HospitalRiyadhSaudi Arabia
  2. 2.Department of PathologyKing Khalid University HospitalRiyadhSaudi Arabia

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