International Urology and Nephrology

, Volume 28, Issue 2, pp 211–214 | Cite as

Effect of digital rectal examination on plasma prostate-specific antigen (PSA)

  • S. Dutkiewicz
  • K. Stępień
  • A. Witeska


Presented are results of determination of plasma PSA before, 1 and 24 hours and 3 weeks after digital rectal examination (DRE) in 130 patients with prostatic adenoma (BPH). Mean pre-examination PSA level was 8.5 ng/ml (max. 27.0 ng/ml, min 0.3 ng/ml, SD=6.2). PSA rose at 1 and 24 hr post-DRE: 9.4 ng/ml (max. 28.9 ng/ml, min 0.5 ng/ml, SD=6.7) and 10.7 ng/ml (max. 28.0 ng/ml, min 0.5 ng/ml, SD=7.9), respectively.

Conclusion: in patients with prostatic adenoma DRE is followed by a rise in plasma PSA, which returns almost to baseline values by 3 weeks.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Dutkiewicz, S., Stlpień, K., Witeska, A.: Diagnostic value of prostate specific antigen (PSA) in comparison to prostatic acid phosphatase (PAP) in prostatic cancer and adenoma.Wiad. Lek., 45, 750 (1992).PubMedGoogle Scholar
  2. 2.
    Dutkiewicz, S., Stawarz, B., Łypka, A., Zieliński, H.: The prognostic value of prostate-specific antigen and prostatic acid phosphatase in serum of patients with prostate cancer after orchidectomy.Int. Urol. Nephrol., 24, 409 (1992).PubMedGoogle Scholar
  3. 3.
    Marczyńska, A., Kulpa, J.: Prostate-specific antigen (PSA) in patients with prostate cancer.Urol. Pol., 45, 69 (1992).Google Scholar
  4. 4.
    Oesterling, J. E.: Prostate-specific antigen: A critical assessment of the most useful tumor marker for adenocarcinoma of the prostate.J. Urol., 145, 907 (1991).PubMedGoogle Scholar
  5. 5.
    Catalona, W. J., Smith, D. S., Ratliff, T. L., Dodds, K. M., Coplen, D. E., Yuan, J. J. J., Petros, J. A., Andriole, G. L.: Measurement of prostate-specific antigen in serum as a screening test for prostate cancer.N. Engl. J. Med., 324, 1156 (1991).PubMedCrossRefGoogle Scholar
  6. 6.
    Correspondence: Measurement of prostate-specific antigen as a screening test for prostate cancer.N. Engl. J. Med., 325, 963 (1991).Google Scholar
  7. 7.
    Shearer, R. J.: Prostatic specific antigen.Br. J. Urol., 67, 1 (1991).PubMedCrossRefGoogle Scholar

Copyright information

© Akadémiai Kiadó 1996

Authors and Affiliations

  • S. Dutkiewicz
    • 1
  • K. Stępień
    • 1
  • A. Witeska
    • 1
  1. 1.Department of Urology, Central Clinical Hospital, Health Administration of the CapitalMinistry of Internal AffairsWarsawPoland

Personalised recommendations