International Urology and Nephrology

, Volume 21, Issue 1, pp 97–104 | Cite as

Immunoperoxidase autopsy study of crescentic glomerulonephritis with extracapillary proliferation

  • T. Tóth
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Abstract

Twenty-five cases of extracapillary crescentic glomerulonephritis were examined immunohistologically. The peroxidase-antiperoxidase (PAP) method was used, the presence of immunoglobulin, complement factors and fibrin was analysed and glomerular positivity was found in all but two cases. Two types of reaction could be discerned: linear and granular, which can be considered as evidence of the pathomechanism. Surprisingly, IgG and IgM positivity was seen most frequently. The author emphasizes the importance of immunoperoxidase examination in the renal histology. This method can be easily applied in paraffin-embedded samples and gives many useful information.

Keywords

Glomerulonephritis Glomerular Basement Membrane International Urology Crescentic Glomerulonephritis Membranous Glomerulonephritis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Akadémiai Kiadó 1989

Authors and Affiliations

  • T. Tóth
    • 1
  1. 1.Department of PathologyCounty Hospital SzolnokHungary

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