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International Urology and Nephrology

, Volume 19, Issue 3, pp 231–243 | Cite as

Pathology of ureterorenal units in various ureteral anomalies with particular reference to the genesis of renal dysplasia

  • T. Gotoh
  • T. Koyanagi
  • S. Tokunaka
Article

Abstract

Renal morphology of various congenital ureteral anomalies was investigated to gain further insight into the genesis of associated renal dysplasia. Abnormality in the ureteral bud explains the genesis of renal dysplasia as long as the adjoining ureter is cranially ectopic. In caudal ectopy of either single or duplex system, no difference was found in the histologic quality of kidneys with G and H position orifice. In the single system kidneys of H position orifice, however, occurrence of renal dysplasia was not associated with obstruction, suggesting the operation of the “bud theory” even in single system caudal ectopy.

In anomalies in which the ureteral orifice was not ectopic, it was suggested that renal parenchymal development was impaired by complete, but not by incomplete obstruction.

The association of dysplastic ureter and renal dysplasia was not so frequent as anticipated and the hypodysplastic values of the kidneys with and without dysplastic ureters were similar, suggesting no direct causal relationship between them.

Keywords

International Urology Renal Dysplasia Ureterocele Ectopic Ureter Duplex Kidney 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. 1.
    Bernstein, J.: Developmental abnormalities of the renal parenchyma—renal hypoplasia and dysplasia.Pathol. Annu., 3, 213 (1968).Google Scholar
  2. 2.
    Potter, E. L.: Type II cystic kidney: Early ampullary inhibition. In: E. L. Potter (ed.): Normal and Abnormal Development of the Kidney. Year Book Medical Publishers, Inc., Chicago 1972, Section II-6, pp. 154–181.Google Scholar
  3. 3.
    Mackie, G. G., Stephens, F. D.: Duplex kidneys: A correlation of renal dysplasia with position of the ureteral orifice.J. Urol., 114, 274 (1975).PubMedGoogle Scholar
  4. 4.
    Tokunaka, S., Koyanagi, T., Matsuno, T., Gotoh, T., Tsuji, I.: Paraureteral diverticula: Clinical experience with 17 cases with associated renal dysmorphism.J. Urol., 124, 791 (1980).PubMedGoogle Scholar
  5. 5.
    Wickramasinghe, S. F., Stephens, F. D.: Paraureteral diverticula: Associated renal morphology and embryogenesis.Invest. Urol., 14, 381 (1977).PubMedCrossRefGoogle Scholar
  6. 6.
    Matsuno, T., Tokunaka, S., Koyanagi, T.: Muscular development in the urinary tract.J. Urol., 132, 148 (1984).PubMedGoogle Scholar
  7. 7.
    Ericsson, N. O.: Ectopic ureterocele in infants and children: A clinical study.Acta Chir. Scand., 197 (Suppl.) 1 (1954).Google Scholar
  8. 8.
    Ericsson, N. O., Ivemark, B. I.: Renal dysplasia and pyelonephritis in infants and children. Part I.Arch. Pathol., 66, 255 (1958).Google Scholar
  9. 9.
    Risdon, R. A.: Renal dysplasia.J. Clin. Path., 24, 57 (1971).PubMedGoogle Scholar
  10. 10.
    Schwarz, R. D., Stephens, F. D., Cussen, L. J.: The pathogenesis of renal dysplasia. I. Quantification of hypoplasia and dysplasia.Invest. Urol., 19, 94 (1981).PubMedGoogle Scholar
  11. 11.
    Schwarz, R. D., Stephens, F. D., Cussen, L. J.: The pathogenesis of renal dysplasia. II. The significance of lateral and medial ectopy of the ureteric orifice.Invest. Urol., 19, 97, (1981).PubMedGoogle Scholar
  12. 12.
    Hanna, M. K.: Ureteral structure and ultrastructure. Part V. The dysplastic ureter.J. Urol., 122, 796 (1979).PubMedGoogle Scholar
  13. 13.
    Tokunaka, S., Gotoh, T., Koyanagi, T., Miyabe, N.: Muscle dysplasia in megaureters.J. Urol., 131, 383 (1984).PubMedGoogle Scholar
  14. 14.
    Gibbons, M. D., Cromie, W. J., Duckett, J. W. Jr.: Ectopic vas deferens.J. Urol., 120, 597 (1978).PubMedGoogle Scholar
  15. 15.
    Gotoh, T., Takahashi, Y., Kumagai, A., Tokunaka, S., Koyanagi, T.: Two cases of ectopic ureter opening into the ejaculatory duct: Double vas deferens revisited.J. Urol., 130, 550 (1983).PubMedGoogle Scholar
  16. 16.
    Tokunaka, S., Gotoh, T., Koyanagi, T., Tsuji, I.: Morphological study of the ureterocele: A possible clue to its embryogenesis as evidenced by a locally arrested myogenesis.J. Urol., 126, 726 (1981).PubMedGoogle Scholar
  17. 17.
    Tokunaka, S., Koyanagi, T., Tsuji, I.: Two infantile cases of primary megaloureter with uncommon pathological findings: Ultrastructural study and its clinical implication.J. Urol., 123, 214 (1980).PubMedGoogle Scholar
  18. 18.
    Filmer, R. B., Taxy, J. B.: Cysts of the kidney, renal dysplasia, and renal hypoplasia. In: P. P. Kelalis, L. R. King, A. B. Belman (es): Clinical Pediatric Urology. W. B. Saunders, Co., Philadelphia-London-Toronto 1976. Vol. 2, Chapt. 19, pp. 680–733.Google Scholar
  19. 19.
    Kelalis, P. P., Malek, R.: Infundibulopelvic stenosis.J. Urol., 125, 568 (1981).PubMedGoogle Scholar
  20. 20.
    Beck, A. D.: The effect of intrauterine urinary obstruction upon the development of the fetal kidney.J. Urol., 105, 784 (1971).PubMedGoogle Scholar
  21. 21.
    Tanagho, E. A.: Surgically induced partial urinary obstruction in the fetal lamb. III. Ureteral obstruction.Invest. Urol., 10, 35 (1972).PubMedGoogle Scholar
  22. 22.
    Berman, D. J., Maizels, M.: The role of urinary obstruction in the genesis of renal dysplasia. A model in the chick embryo.J. Urol., 128, 1091 (1982).PubMedGoogle Scholar
  23. 23.
    Henneberry, M. O., Stephens, F. D.: Renal hypoplasia and dysplasia in infants with posterior urethral valves.J. Urol., 123, 912 (1980).PubMedGoogle Scholar
  24. 24.
    Gotoh, T., Morita, H., Tokunaka, S., Koyanagi, T., Tsuji, I.: Single ectopic ureter.J. Urol., 129, 271 (1983).PubMedGoogle Scholar
  25. 25.
    Schwarz, R., Stephens, F. D.: Persisting mesonephric duct: high junction of vas deferens and ureter.J. Urol., 120, 592 (1978).PubMedGoogle Scholar
  26. 26.
    Vordermark, J. S., II: The persisting mesonephric duct syndrome: The description of a new syndrome.J. Urol., 130, 958 (1983).PubMedGoogle Scholar
  27. 27.
    Schnitzer, B.: Ectopic ureteral opening into seminal vesicle: a report of four cases.J. Urol., 93, 576 (1965).PubMedGoogle Scholar
  28. 28.
    Johnson, F. R., Anderson, J. C.: Developmental remnants in an adult human kidney.J. Path. Bact., 66, 39 (1953).PubMedCrossRefGoogle Scholar
  29. 29.
    Schwarz, R. D., Stephens, F. D., Cussen, L. J.: The pathogenesis of renal dysplasia. III. Complete and incomplete urinary obstruction.Invest. Urol., 19, 101 (1981).PubMedGoogle Scholar
  30. 30.
    Tokunaka, S., Koyanagi, T.: Morphologic study of primary non-reflux megaureters with particular emphasis on the role of ureteral sheath and ureteral dysplasia.J. Urol., 128, 399 (1982).PubMedGoogle Scholar

Copyright information

© Akadémiai Kiadó 1987

Authors and Affiliations

  • T. Gotoh
    • 1
  • T. Koyanagi
    • 1
  • S. Tokunaka
    • 1
  1. 1.Hokkaido University School of MedicineSapporoJapan

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