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Lipids

, Volume 23, Issue 11, pp 1032–1036 | Cite as

Investigations of the origin of the furan fatty acids (F-acids)

  • Charles P. Gorst-Allman
  • Volker Puchta
  • G. Spiteller
Articles

Abstract

The possible role of linoleic acid as a biogenetic precursor of the furan fatty acids (F-acids) was investigated in in vivo experiments in the rat, using a C19 analogue of linoleic acid and gas chromatography-mass spectrometry. No evidence of incorporation of this compound into the F-acids was found. Using an improved analysis procedure by converting F-acids into their tetrahydrofuran derivatives (enabling a separation from the large amounts of normal fatty acids), F-acids (F3, F4 and F6) were detected in rat food, correcting earlier results.

Quantification of F-acid intake with food and excretion of furandicarboxylic acids in the urine, suggested the possibility that the F-acids are not produced de novo in the rat, but instead accumulate in tissue after nutritional intake.

Keywords

High Performance Liquid Chromatography Linoleic Acid Normal Fatty Acid Potassium Chloride Solution Ylic Acid 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

GC

gas chromatography

HPLC

high performance liquid chromatography

MS

mass spectrometry

TLC

thin layer chromatography

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Copyright information

© American Oil Chemists’ Society 1988

Authors and Affiliations

  • Charles P. Gorst-Allman
    • 1
  • Volker Puchta
    • 2
  • G. Spiteller
    • 2
  1. 1.National Chemical Research LaboratoryCouncil for Scientitic and Industrial ResearchPretoriaRepublic of South Africa
  2. 2.Lehrstuhl für Organische Chemie I der Universität BayreuthBayreuthFederal Republic of Germany

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