, Volume 15, Issue 12, pp 1062–1063 | Cite as

Occurrence of squalene in skin surface lipids of the otter, the beaver and the kinkajou

  • Jane S. Lindholm
  • Donald T. Downing


In a previous survey of the skin surface lipids of 46 mammalian species, it was found that only 3, the otter, the beaver and the kinkajou, contained components with chromatographic mobility similar to squalene, and in each case, this material was the predominant constituent. The materials in question have now been isolated from each of these species and identified as squalene by thin layer chromatography, gas chromatography and infrared spectroscopy. The occurrence of squalene in the surface lipids of these particular species cannot be explained on the basis of either their evolutionary relationship or ecological niche.


Squalene Surface Lipid Glyceryl Ether Thin Layer Chromatogram Thin Layer Chromatog 
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  1. 1.
    Nicolaides, N., H.C. Fu, and G.R. Rice, J. Invest. Dermatol. 51:83 (1968).PubMedCrossRefGoogle Scholar
  2. 2.
    Nikkari, T., J. Invest. Dermatol. 62:257 (1974).PubMedCrossRefGoogle Scholar
  3. 3.
    Downing, D.T., in “Chemistry and Biochemistry of Natural Waxes,” edited by P.E. Kolattukudy, Elsevier, New York, 1976, pp. 17–48.Google Scholar
  4. 4.
    Nikkari, T., Scand. J. Clin. Lab. Invest. 17 (Suppl. 85):1–140 (1965).PubMedGoogle Scholar
  5. 5.
    Wilkinson, D.I., and M.A. Karasek, J. Invest. Dermatol. 47:449 (1966).PubMedCrossRefGoogle Scholar
  6. 6.
    Lindholm, J.S., J.M. McCormick, S.W. Colton VI and D.T. Downing, Comp. Biochem. Physiol., in press.Google Scholar
  7. 7.
    Downing, D.T., J. Chromatogr. 38:91 (1968).PubMedCrossRefGoogle Scholar
  8. 8.
    Downing, D.T., and A.M. Stranieri, J. Chromatogr. 192:208 (1980).CrossRefGoogle Scholar

Copyright information

© American Oil Chemists’ Society Society 1980

Authors and Affiliations

  • Jane S. Lindholm
    • 1
  • Donald T. Downing
    • 1
  1. 1.Department of DermatologyUniversity of Iowa College of MedicineIowa City

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