, Volume 12, Issue 4, pp 407–408 | Cite as

Identification of thetrans isomers of octadecenoic acid in human milk

  • Mary Frances Picciano
  • Edward G. Perkins
Short Communication


The presence oftrans octadecenoic acid isomers was detected and analyzed in 24 hr pooled samples of human milk. Amounts of thetrans isomers of the C18 monoenes ranged from 2% to 4% of the total fatty acids. For purposes of comparison, three commonly used brands of infant formula were also analyzed and found to contain 0.1% to 1.3% oftrans monoene isomers. Data indicate that breast-fed and bottle-fed infants are receiving minimal levels oftrans fatty acids via milk.


  1. 1.
    Insull, W., J. Hirsch, T. James, and E.H. Ahrens, J. Clin. Invest. 38:443 (1959).PubMedGoogle Scholar
  2. 2.
    Insull, W., and E.H. Ahrens, Bioch. J. 72:27 (1959).Google Scholar
  3. 3.
    Risek, R.L., B. Friend, and L. Page, JAOCS 51:244 (1974).Google Scholar
  4. 4.
    Guthrie, H.A., D. Skeehe, and M.F. Picciano, J. Pediat. 90:39 (1977).PubMedCrossRefGoogle Scholar
  5. 5.
    Kummerow, F.A., J. Food Sci. 40:12 (1975).Google Scholar
  6. 6.
    Folch, J., M. Lees, and G.H. Sloane-Stanley, J. Biol. Chem. 191:833 (1951).PubMedGoogle Scholar
  7. 7.
    Ottenstein, D.M., D.A. Barlley, and W.R. Supina, J. Chromatogr. 119:401 (1976).PubMedCrossRefGoogle Scholar
  8. 8.
    Perkins, E.G., T. McCarthy, M. O’Brian, and F.A. Kummerow, JAOCS (submitted for publication).Google Scholar
  9. 9.
    Vergroesen, A.J., Proc. Nutr. Soc. 31:323 (1972).PubMedCrossRefGoogle Scholar
  10. 10.
    Mattson, F.H., E.J. Hollenbach, and A.M. Kligman, Am. J. Clin. Nutr. 28:726 (1975).PubMedGoogle Scholar

Copyright information

© American Oil Chemists’ Society 1977

Authors and Affiliations

  • Mary Frances Picciano
    • 1
  • Edward G. Perkins
    • 2
  1. 1.School of Human Resources and Family Studies Division of Foods and NutritionUniversity of IllinoisUrbana
  2. 2.Department of Food Science Burnsides Research LaboratoryUniversity of IllinoisUrbana

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