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Bulletin of Experimental Biology and Medicine

, Volume 125, Issue 4, pp 345–347 | Cite as

Prediction of the resistance to hypoxia on the basis of modifications of the adenine nucleotide system

  • A. N. Moshkova
  • V. E. Stefanov
  • E. M. Khvatova
  • S. N. Lyzlova
Biophysics and Biochemistry

Abstract

An empirical dependence allowing one to identify rhythmic fluctuations of stable and unstable state in respect of hypoxia in the process of adaptation has been developed on the basis of long-term investigation of changes in brain content of adenine nucleotides upon “hypobaric training” of rabbits. The function approximating this dependence enables one to predict the effective number of “hypobaric training” sessions providing for the adaptive reaction.

Key Words

hypoxia AMP ATP energy metabolism adaptation 

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Copyright information

© Plenum Publishing Corporation 1998

Authors and Affiliations

  • A. N. Moshkova
    • 1
    • 2
    • 3
  • V. E. Stefanov
    • 1
    • 2
    • 3
  • E. M. Khvatova
    • 1
    • 2
    • 3
  • S. N. Lyzlova
    • 1
    • 2
    • 3
  1. 1.Department of BiochemistrySt. Petersburg UniversityUSSR
  2. 2.Department of Applied MathematicsNizhnii Novgorod State Technical UniversityUSSR
  3. 3.Department of BiochemistryNizhnii Novgorod Medical AcademyUSSR

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