Abstract
Reformatsky-type addition of esters of α-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)5 and an activating agent (CBrCl3 or I2) afforded the corresponding esters of β-hydroxy acids in good yields. Possible reaction mechanisms are discussed.
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Translated fromIzvestiya Akademii Nauk. Seriya Khimicheskaya, No. 6, pp. 1132–1138, June, 1999.
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Terent'ev, A.B., Vasil'eva, T.T., Kuz'mina, N.A. et al. Reformatsky-type addition of esters of α-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)5 . Russ Chem Bull 48, 1121–1127 (1999). https://doi.org/10.1007/BF02496013
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DOI: https://doi.org/10.1007/BF02496013