, Volume 46, Issue 1–2, pp 67–71 | Cite as

Analysis of some anhydrides as their corresponding acids by capillary electrophoresis

  • Y. He
  • H. K. Lee


The potential of capillary electrophoresis for the indirect determination of anhydrides was demonstrated by the analysis of five closely-related anhydrides as their corresponding acids. Direct analysis of such substances is generally difficult because of their susceptibility to hydrolysis. In this work anhydrides were first hydrolyzed in water, hydrolysis being monitored using micellar electrokinetic chromatography (MEKC) which separated neutral anhydrides and anions of corresponding acids. After hydrolysis, separation of the acids was quickly achieved within two minutes by reversed electroosmotic-flow, capillary electrophoresis (REF-CE), with UV detection at 210 nm.

Key Words

Capillary electrophoresis Reversed electroosmotic flow Organic acids Anhydrides 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. [1]
    J. W. Jorgenson, K. D. Lukacs, Anal. Chem.53, 1298 (1981).Google Scholar
  2. [2]
    S. Terabe, K. Otsuka, K. Ichikawa, T. Ando, Anal. Chem.56, 113 (1984).CrossRefGoogle Scholar
  3. [3]
    S. Terabe, E. R. Barnhart, B. L. Karger, K. Hosoya, J. Chromatogr.516, 23 (1990).CrossRefGoogle Scholar
  4. [4]
    F. E. P. Mikkers, F. M. Everaerts, Th. P. E. Verheggety, J. Chromatogr.169, 11 (1979).CrossRefGoogle Scholar
  5. [5]
    M. J. George, C. C. King, A. B. Jeffrey, J. L. Haleeim, J. Chromatogr. A653, 321 (1993).CrossRefGoogle Scholar
  6. [6]
    Y. M. Liu, S. J. Sheu, J. Chromatogr. A665, 239 (1994).CrossRefGoogle Scholar
  7. [7]
    P. M. Hergenrother, D. Wilson, H. D. Stezeberger, (Editors), Polyimides, Chapman & Hall, New York, 1990.Google Scholar
  8. [8]
    A. J. Domb, S. Amselem, M. Maniar, Adv. Polym. Sci.107, 93 (1993).CrossRefGoogle Scholar
  9. [9]
    N. H. Proctor, J. P. Hughes, Chemical Hazards of the Work-place, J. B. Lippincott, Philadelphia, 1978, p. 421.Google Scholar
  10. [10]
    M. M. Koton, V. V. Kurdiavats, V. M. Lsvetlichy, Polyimides-Synthesis, characterization and Applications, Vol. 2, Plenum Press, New York, 1984.Google Scholar
  11. [11]
    W. Heyde, Fresenius’ J. Anal. Chem.320, 667 (1985).CrossRefGoogle Scholar
  12. [12]
    S. D. Patterson, R. E. A. Escott, High Perform. Polym.2, 197 (1990).Google Scholar
  13. [13]
    A. J. Domb, J. Chromatogr. A673, 31 (1994).CrossRefGoogle Scholar
  14. [14]
    K. K. Verma, P. Tuagi, Anal. Chem.56, 2157 (1984).CrossRefGoogle Scholar
  15. [15]
    J. Bartos, Talanta.27, 583 (1980).CrossRefGoogle Scholar
  16. [16]
    S. D. Richardson, A. D. Thruston, Jr., T. W. Collette, Environ. Sci. Technol.28, 592 (1994).CrossRefGoogle Scholar
  17. [17]
    D. E. Burton, M. J. Sepamia, M. P. Maskarinec, J. Chromatogr. Sci.25, 514 (1987).Google Scholar
  18. [18]
    D. E. Burton, M. J. Sepaniak, M. P. Maskarinec, J. Chromatogr. Sci.24, 347 (1986).Google Scholar
  19. [19]
    H. Nishi, N. Tsumagari, T. Kakimoto, S. Terabe, J. Chromatogr.465, 331 (1989).CrossRefGoogle Scholar
  20. [20]
    X. Huang, J. A. Luckey, M. J. Gordon, Anal. Chem.61, 766 (1989).CrossRefGoogle Scholar
  21. [21]
    B. F. Kenney, J. Chromatogr.546, 423 (1991).CrossRefGoogle Scholar
  22. [22]
    X. Huan, R. N. Zare, S. Sloss, A. G. Ewing, Anal. Chem.63, 89 (1991).Google Scholar
  23. [23]
    M. T. Ackermans, F. M. Everaerts, J. L. Beckers, J. Chromatogr.606, 229 (1992).CrossRefGoogle Scholar
  24. [24]
    S. Terabe, K. Ishikavoa, K. Utsuka, A. Tsuchiya, T. Andro, presented at the 26th International Liquid Chromatography Symposium, Kyoto, Japan, January 25–26, 1983.Google Scholar
  25. [25]
    T. Kaneta, S. Tanak, M. Taga, H. Yoshida, Anal. Chem.64, 798 (1992).CrossRefGoogle Scholar
  26. [26]
    T. Kaneta, S. Tanaka, M. Taga, J. Chromatogr. A653, 313 (1993).CrossRefGoogle Scholar
  27. [27]
    G. M. Janini, K. C. Chan, J. A. Barnes, G. M. Mushik, H. J. Issaa, J. Chromatogr. A653, 321 (1993).CrossRefGoogle Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1997

Authors and Affiliations

  • Y. He
    • 1
  • H. K. Lee
    • 1
  1. 1.Department of ChemistryNational University of SingaporeKent RidgeRepublic of Singapore

Personalised recommendations