Chromatographia

, Volume 52, Issue 1–2, pp 22–26 | Cite as

Quantitative analysis of the compounds in synthesis mixtures of 2,2-dimethyl-3-hydroxypropionaldehyde by RP-HPLC and GC

  • E. Koivusalmi
  • H. Hakanpää-Laitinen
  • E. Haatainen
  • T. Saarela
  • I. Kilpeläinen
Originals Column Liquid Chromatography
Received:
Revised:
Accepted:

Summary

RP-HPLC and GC methods are described for the determination of the compounds in synthesis mixtures of 2,2-dimethyl-3-hydroxypropionaldehyde (DHPAL). Special attention is paid to the analysis of DHPAL. Conditions for analysis are developed so that no derivatization is needed despite the equilibrium reactions typical of hydroxy aldehydes. Different solvent matrices, pH and sample concentrations are tested in sampling and analysis. Linearity of the calibration lines and precision of the methods are evaluated for all compounds. Detection limits of different compounds are calculated for both methods.

Key Words

Column liquid chromatography Gas chromatography Hydroxy aldehydes 
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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 2000

Authors and Affiliations

  • E. Koivusalmi
    • 1
  • H. Hakanpää-Laitinen
    • 1
  • E. Haatainen
    • 1
  • T. Saarela
    • 1
  • I. Kilpeläinen
    • 2
  1. 1.Fortum Oil and Gas OyScientific Services, Analytical ResearchPorvooFinland
  2. 2.Institute of BiotechnologyUniversity of HelsinkiFinland

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