Journal of Medical Ultrasonics

, 29:155

Elastography: Imaging the elastic properties of soft tissues with ultrasound

  • Jonathan Ophir
  • S. Kaisar Alam
  • Brian S. Garra
  • Faouzi Kallel
  • Elisa E. Konofagou
  • Thomas Krouskop
  • Christopher R. B. Merritt
  • Raffaella Righetti
  • Remi Souchon
  • Seshadri Srinivasan
  • Tomy Varghese
Review Article


Elastography is a method that can ultimately generate several new kinds of images, called elastograms. As such, all the properties of elastograms are different from the familiar properties of sonograms. While sonograms convey information related to the local acoustic backscatter energy from tissue components, elastograms relate to its local strains, Young's moduli or Poisson's ratios. In general, these elasticity parameters are not directly correlated with sonographic parameters, i.e. elastography conveys new information about internal tissue structure and behavior under load that is not otherwise obtainable. In this paper we summarize our work in the field of elastography over the past decade. We present some relevant background material from the field of biomechanics. We then discuss the basic principles and limitations that are involved in the production of elastograms of biological tissues. Results from biological tissues in vitro and in vivo are shown to demonstrate this point. We conclude with some observations regarding the potential of elastography for medical diagnosis.


elastography ultrasound 


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Copyright information

© The Japan Society of Ultrasonics in Medicine 2002

Authors and Affiliations

  • Jonathan Ophir
    • 1
    • 2
  • S. Kaisar Alam
    • 1
    • 3
  • Brian S. Garra
    • 4
  • Faouzi Kallel
    • 1
  • Elisa E. Konofagou
    • 1
    • 5
  • Thomas Krouskop
    • 6
  • Christopher R. B. Merritt
    • 7
  • Raffaella Righetti
    • 1
    • 2
  • Remi Souchon
    • 8
  • Seshadri Srinivasan
    • 1
    • 2
  • Tomy Varghese
    • 1
    • 9
  1. 1.The University of Texas Medical School at HoustonHoustonUSA
  2. 2.Department of ECEThe University of HoustonHoustonUSA
  3. 3.Riverside Research InstituteNew YorkUSA
  4. 4.Fletcher Allen Medical CenterUniversity of VermontBurlingtonUSA
  5. 5.Brigham and Women's HospitalBostonUSA
  6. 6.Baylor College of MedicineHoustonUSA
  7. 7.Thomas Jefferson UniversityPhiladelphiaUSA
  8. 8.l'Institut National de la Sante et de la Recherche Médicale (INSERM) Unité 556LyonFrance
  9. 9.University of WisconsinMadisonUSA

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