The Japanese journal of surgery

, Volume 19, Issue 4, pp 480–484 | Cite as

A case of metastasis from gastric cancer to the thyroid gland

  • Akira Yoshida
  • Akira Imamura
  • Hideyuki Tanaka
  • Minoru Hirano
  • Hiroshi Kamma
  • Ei Ueno
  • Hiroki Ushio
  • Yuji Aiyoshi
  • Shugo Soeda
Case Reports

Abstract

Metastatic tumors in the thyroid gland are rarely seen in clinical practice. This report describes a case of metastasis from gastric cancer to the thyroid, found five years after removal of the primary gastric lesion. The patient had a large thyroid mass extending to the mediastinum, but there were no obvious metastatic lesions anywhere except in the thyroid. Subtotal thyroidectomy was performed and histological examination revealed the same findings as those of the original gastric cancer. Of additional interest are the findings that led us to believe this metastatic tumor produced alpha-fetoprotein. Seven months following the operation, the patient died suddenly and, although it is difficult to say whether the patient’s survival was prolonged, we believe that the thyroid surgery gave him considerable palliation.

Key words

gastric cancer metastasis thyroid 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Coman DR, de Long RP, McCutcheon M. The distribution of tumors in various organs in relation to distribution of arterial emboli. Cancer Res 1951; 11: 648–651.PubMedGoogle Scholar
  2. 2.
    Abrahms HL, Spiro R, Goldstein N. Metastases in carcinoma; analysis of 1000 autopsied cases. Cancer 1950; 3: 74–85.CrossRefGoogle Scholar
  3. 3.
    Willis RA. Metastatic tumors in the thyroid gland. Am J Pathol 1931; 7: 187–205.PubMedGoogle Scholar
  4. 4.
    Shimaoka S, Sokal JE, Pickren JW. Metastatic neoplasms in the thyroid gland. Cancer 1962; 11: 557–565.CrossRefGoogle Scholar
  5. 5.
    Silverberg SG, Vidone RA. Metastatic tumors in the thyroid. Pacif Med Surg 1966; 74: 175–180.Google Scholar
  6. 6.
    Elliott RHE Jr, Frantz VR. Metastatic carcinoma masquerading as primary thyroid cancer: A report of authors’ 14 cases. Ann Surg 1960; 151: 551–561.PubMedGoogle Scholar
  7. 7.
    Wychulis AR, Beahrs OH, Woolner LB. Metastasis of carcinoma to the thyroid gland. Ann Surg 1964; 160: 169–177.PubMedCrossRefGoogle Scholar
  8. 8.
    Pillay SP, Angorn IB, Baker LW. Tumor metastasis to the thyroid gland. S Afr Med J 1977; 51: 509–512.PubMedGoogle Scholar
  9. 9.
    Ericsson M, Blökklund A, Cederquist E, Ingemansson S, Akerman M. Surgical treatment of metastatic disease in the thyroid gland. J Surg Oncol 1981; 17: 15–23.PubMedGoogle Scholar
  10. 10.
    Czech JM, Lichtor TR, Carney JA, van Heerden JA. Neoplasms metastatic to the thyroid gland. Surg Gynecol Obstet 1982; 155: 503–505.PubMedGoogle Scholar
  11. 11.
    McCabe DP, Farrar WB, Petkov TM, Finkelmeier W, O’wyer P, James A. Clinical and pathologic correlations in disease metastatic to the thyroid gland. Am J Surg 1985; 150: 519–523.PubMedCrossRefGoogle Scholar
  12. 12.
    Mortensen JD, Woolner LB, Bennett WA. Secondary malignant tumors of the thyroid gland. Cancer 1956; 9: 306–309.PubMedCrossRefGoogle Scholar
  13. 13.
    Kobayashi K, Yashiro T, Suzuki A, Manabe Y, Ozaki O, Ito K. Two cases of metastatic tumor to the thyroid gland. Nihon Rinsho Geka Gakkai Zasshi (J Jpn Soc Clin Surg) 1988; 49: 64–69. (English Abstr.)Google Scholar
  14. 14.
    Takashima S, Saeki H, Morimaki S, Yamamoto Y. A study of metastatic thyroid tumors found at autopsy. Gan no Rinsho (Jap J Cancer Clin) 1984; 30: 880–884 (English Abst.)PubMedGoogle Scholar
  15. 15.
    Batson OV. The function of the vertebral veins and their role in the spread of metastases. Ann Surg 1940; 112: 138–149.PubMedGoogle Scholar
  16. 16.
    Kodama T, Kameya T, Horota T, Shimosato Y, Ohkura H, Mukojima T, Kitaoka H. Production of alpha-fetoprotein, normal serum proteins, and human chorionic gonadotropin in stomach cancer: Histologic and immunohistochemical analyses of 35 cases. Cancer 1981; 48: 1647–1655.PubMedCrossRefGoogle Scholar
  17. 17.
    Ishikura H, Kirimoto K, Shamoto M, Miyamoto Y, Yamagiwa H, Itoh T, Aisawa M. Hepatoid adenocarcinoma of the stomach. Cancer 1986; 58: 119–126.PubMedCrossRefGoogle Scholar
  18. 18.
    Watts NB. Carcinoma metastatic to the thyroid: Prevalence and diagnosis by fine-needle aspiration cytology. Am J Med Sci 1987; 293: 13–17.PubMedGoogle Scholar
  19. 19.
    Lasser A, Rothman JG, Calamia VJ. Renal-cell carcinoma metastatic to the thyroid: Aspiration cytology and histologic findings. Acta Cytol 1985; 29: 856–858.PubMedGoogle Scholar

Copyright information

© The Japan Surgical Society 1989

Authors and Affiliations

  • Akira Yoshida
    • 1
  • Akira Imamura
    • 1
  • Hideyuki Tanaka
    • 1
  • Minoru Hirano
    • 1
  • Hiroshi Kamma
    • 2
  • Ei Ueno
    • 1
  • Hiroki Ushio
    • 1
  • Yuji Aiyoshi
    • 1
  • Shugo Soeda
    • 1
  1. 1.The Department of Surgery, Institute of Clinical MedicineUniversity of TsukubaTsukubaJapan
  2. 2.The Department of Pathology, Institute of Basic Medical ScienceUniversity of TsukubaTsukubaJapan

Personalised recommendations