Acquired B antigen and polyagglutination in a patient with gastric cancer

  • Sho Matsushita
  • Takashi Imamura
  • Tomohiro Mizuta
  • Motosuke Hanada
Short Communications

Abstract

Erythrocytes from a patient with blood type of A1 became nongenetically reactive with A (anti-B) serum, following the development of gastric cancer. Transient polyagglutinability was also apparent. Thein vitro acetylation of the erythrocyte antigens abolished both the acquired B antigen and the polyagglutination. Although incubation of the heterologous type A1 erythrocytes with the patient's serum did not produce B antigen, deacetylase activity in the serum seems to relate to the acquired B antigen. In this case, either ileus as a result of metastatic adenocarcinoma of the stomach, or urinary tract infections could be the cause of the acquired B antigen.

Key Words

blood type acquired B antigen deacetylase 

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Copyright information

© The Japan Surgical Society 1983

Authors and Affiliations

  • Sho Matsushita
    • 1
  • Takashi Imamura
    • 1
  • Tomohiro Mizuta
    • 2
  • Motosuke Hanada
    • 2
  1. 1.First Department of Internal Medicine, Faculty of MedicineKyushu UniversityFukuokaJapan
  2. 2.Sanshinkai Hara HospitalFukuokaJapan

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