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Chromatographia

, Volume 47, Issue 7–8, pp 470–474 | Cite as

Synthesis of molecular imprinted polymer networks

  • S. Rimmer
Papers Presented at: Affinity Chromatography Conference, Cambridge (UK), July 1–3, 1997 Review Paper

Summary

The article covers the methods that are currently available for the preparation of molecularly imprinted polymers. The disadvantages of the conventional grinding of bulk polymerized blocks of imprinted polymer are first identified. The newer methods are divided into four sections: suspension polymerization; modified surfaces; polymer colloids and finally miscellaneous techniques such as the use of linear polymers. Each alternative method is compared with the grinding method and the relative advantages and disadvantages identified.

Key Words

Affinity chromatography Polymerization Imprinted polymer networks Colloid Silica 

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References

  1. [1]
    a G. Wulff, A, Sarhan, K. Zarbrocki, Tet. Lett. 4329 (1973);b for a review see G.Wulff, Angew. Chem. Int. Ed Engl.34, 1812, (1995).Google Scholar
  2. [2]
    B. Sellergreen, M. Lepisto, K. Mossbach, J. Am. Chem. Soc.110, 5853 (1988).CrossRefGoogle Scholar
  3. [3]
    B. Sellergen, J. Chromatogr. A.673, 133 (1994).CrossRefGoogle Scholar
  4. [4]
    B. Sellergen, Anal. Chem.66, 1578, (1994).CrossRefGoogle Scholar
  5. [5]
    K. Hosaya, K. Yoshizako, N. Tanaka, K. Kimata, K. Kimata, T. Araki, J. Haginaka, Chem. Lett. 1437 (1994).Google Scholar
  6. [6]
    K. Mosbach, A. G. Mayes, Anal. Chem.68, 3769 (1996).CrossRefGoogle Scholar
  7. [7]
    F. H. Dickey, Proc. Nat. Acad. Sci.35, 227 (1949).CrossRefGoogle Scholar
  8. [8]
    F. H. Dickey, J. Phys. Chem.59, 695 (1955).CrossRefGoogle Scholar
  9. [9]
    O. Norlow, M. Glad, M. Mossbach, J. Chromatogr.299, (1984)Google Scholar
  10. [10]
    G. Wulff, M. Oberkobusch, M. Minarik, React. Polym.3, 261 (1985).Google Scholar
  11. [11]
    M. Glad, O. Norrlow, B. Sellergren, N. Siegbahn, K. Mossbach, J. Chromatogr347, 11 (1985).CrossRefGoogle Scholar
  12. [12]
    O. Norrlow, M.-O. Masson, K. Mossbach, J. Chromatogr396, 374 (1987).CrossRefGoogle Scholar
  13. [13]
    T. Shimada, K. Nakanishi, K. Morihara, Bull. Chem. Soc. Jap.65, 954 (1992).CrossRefGoogle Scholar
  14. [14]
    K. Morihara, S. Doi, M. Takiguichi, T. Shimada, Bull. Chem. Soc. Jap.66, 2977 (1993).Google Scholar
  15. [15]
    K. Morihara, S. Doi, M. Takiguchi, T. Shimada, Bull. Chem. Soc. Jap.66, 2977 (1993).Google Scholar
  16. [16]
    T. Matsuishi, T. Shimada, K. Morihara, Bull. Chem. Soc. Jap.67, 748 (1994).CrossRefGoogle Scholar
  17. [17]
    K. Morihara, M. Takiguchi, T. Shimada, Bull. Chem. Soc. Jap.67, 1078 (1994).CrossRefGoogle Scholar
  18. [18]
    K. Morihara, S. Kawasaki, M. Kofuji, T. Shimada, Bull. Chem. Soc. Jap.66, 906 (1993).CrossRefGoogle Scholar
  19. [19]
    T. Shimada, R. Hirose, K. Morihara, Bull. Chem. Soc. Jap.67, 227 (1994).CrossRefGoogle Scholar
  20. [20]
    K. Morihara, T. Iijima, H. Usui, T. Shimada, Bull. Chem. Soc. Jap.66, 3047 (1993).Google Scholar
  21. [21]
    S. Vidyasankar, P. K. Dhal, S. D. Plinkett, F. H. Arnold, Biotech. Bioeng.48, 431 (1995).CrossRefGoogle Scholar
  22. [22]
    Ky. Yu, K. Tsukagoshi, M. Maeda, M. Takagi, Anal. Sci.8, 701 (1992).Google Scholar
  23. [23]
    H. Kido, T. Miyajima, K. Tsukagoshi, M. Maeda, M. Takagi, Anal. Sci.8, 749 (1992).Google Scholar
  24. [24]
    H. Kido, H. Sonoda, K. Tsukagoshi, M. Maeda, M. Takagi, H. Maki, T. Mliyajima, Kobunshi Ronbunshu50, 403 (1993).Google Scholar
  25. [25]
    K. Uezu, H. Nakamura, M. Goto, M. Murata, M. Maeda, M. Takagi, F. Nakashio, J. Chem. Eng. Jap.27, 436, (1994).CrossRefGoogle Scholar
  26. [26]
    M. Maeda, M. Murata, K. Tsukagoshi, M. Takagi, Anal. Sci.10, 113 (1994).Google Scholar
  27. [27]
    M. Murata, S. Hiyiya, M. Maeda, M. Takagi, Bull. Chem. Soc. Jap.69, 637 (1996).CrossRefGoogle Scholar
  28. [28]
    Y. Koide, H. Senba, H. Shosenji, M. Maeda, M. Takagi, Bull. Chem. Soc. Jap.69, 125 (1996).CrossRefGoogle Scholar
  29. [29]
    I. Fujiwara, M. Maeda, M. Takagi, Anal. Sci.12, 545 (1996).Google Scholar
  30. [30]
    M. Yoshida, K. Uezu, M. Goto, F. Nakashio, J. Chem. Eng. Jap.29, 174 (1996).CrossRefGoogle Scholar
  31. [31]
    M. Yoshida, K. Uezu, M. Goto, F. Nakashio, Abstracts Of Papers Of The ACS25, 213, (1997).Google Scholar
  32. [32]
    K. Uezu, M. Goto, F. Nakashio, Abstracts Of Papers Of The ACS213, 101 (1997).Google Scholar
  33. [33]
    T. Hara, M. Yoshida, K. Uezu, M. Goto, F. Nakashio. Abstracts Of Papers Of The ACS,213, 30 (1997).Google Scholar
  34. [34]
    L. Braco, K. Dabulis, A. M. Klibanov, Proc. Nat. Acad. Sci.87, 274 (1990).CrossRefGoogle Scholar
  35. [35]
    K. Dabulis, A. M. Klibanov, Biotechnol. Bioeng.39, 176 (1992).CrossRefGoogle Scholar
  36. [36]
    M. Stahl, M.-O. Mansson, K. Mossbach, Biotechnol. Lett.12, 161 (1990).CrossRefGoogle Scholar
  37. [37]
    M. Stahl, U. Jeppsson-Wistrand, M.-O. Mansson, K. Mossbach, J. Am. Chem. Soc.113, 9366 (1991).CrossRefGoogle Scholar
  38. [38]
    Y. Ohya, J. Miyaoka, T. Ouchi, Makromol. Rap. Comm.17, 871 (1996).CrossRefGoogle Scholar
  39. [39]
    J. Matsui, T. Kato, T. Takeuchi, M. Suzuki, K. Yokoyama, E. Tamiya, I. Karube, Anal. Chem.65, 2223 (1993).Google Scholar

Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1998

Authors and Affiliations

  • S. Rimmer
    • 1
  1. 1.The Polymer CentreLancaster UniversityLancasterUK

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