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Chromatographia

, Volume 47, Issue 7–8, pp 465–469 | Cite as

Applications of molecularly imprinted materials as selective adsorbents: Emphasis on enzymatic equilibrium shifting and library screening

  • O. Ramström
  • L. Ye
  • M. Krook
  • K. Mosbach
Papers Presented at: Affinity Chromatography Conference, Cambridge (UK), July 1–3, 1997 Original

Summary

Molecular imprinting is an attractive method for producing highly selective adsorbents, and several new and potentially useful applications based on molecularly imprinted polymers (MIPs) have been described in recent years. In this article, we highlight some of the areas where these materials have found application, and also describe some new fields of application where the selectivities of imprinted materials can be gainfully employed, for example as binding matrices in the screening of combinatorial libraries, and as auxiliary agents in enzymatic syntheses.

Key Words

Column liquid chromatography Affinity chromatography Molecular imprinting Molecular recognition Combinatorial libraries 

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Copyright information

© Friedr. Vieweg & Sohn Verlagsgesellschaft mbH 1998

Authors and Affiliations

  • O. Ramström
    • 1
  • L. Ye
    • 1
  • M. Krook
    • 1
  • K. Mosbach
    • 1
  1. 1.Pure and Applied Biochemistry, Center for Chemistry and Chemical EngineeringLund UniversityLundSweden

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