The genetics of position — effect variegation modifying loci inDrosophila melanogaster

  • G. Wustmann
  • J. Szidonya
  • H. Taubert
  • G. Reuter


The dose dependent effects of position-effect variegation (PEV) modifying genes were studied in chromosome arms2L, 2R and3R. Four groups of PEV modifying genes can be distinguished: haplo-abnormal suppressor and enhancer loci with or without a triplo-effect. using duplications four triplo-abnormal suppressor and four triplo-abnormal enhancer functions were localized. In two cases we proved that these functions correspond to a converse haplo-abnormal one. Altogether 43 modifier loci were identified. Most of these loci proved not to display significant triplo-effects (35). The group of haplo-abnormal loci with a triplo-effect may represent genes which play an important role in heterochromatin packaging.

Key words

Drosophila melanogaster Position-effect variegation Modifier loci Gene dosage effects 


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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • G. Wustmann
    • 1
  • J. Szidonya
    • 2
  • H. Taubert
    • 1
  • G. Reuter
    • 1
  1. 1.Department of Genetics, Section BiosciencesMartin Luther University HalleHalle/S.
  2. 2.Institute of Genetics, Biological Research CenterHungarian Academy of SciencesSzegedHungary

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