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Bulletin of Mathematical Biology

, Volume 50, Issue 6, pp 579–593 | Cite as

On the validity of the steady state assumption of enzyme kinetics

  • Lee A. Segel
Article

Abstract

By estimating relevant time scales, a simple new condition can be found that ensures the validity of the steady state assumption for a standard enzyme-substrate reaction. The generality of the approach is demonstrated by applying it to the determination of validity criteria for the steady state assumption applied to an enzyme-substrate-inhibitor system.

Keywords

Slow Time Scale Steady State Approximation Singular Perturbation Theory Steady State Assumption Enzyme Kinetics 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Society for Mathematical Biology 1988

Authors and Affiliations

  • Lee A. Segel
    • 1
  1. 1.Department of Applied Mathematics and Computer ScienceThe Weizmann Institute of ScienceRehovotIsrael

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