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Bulletin of Mathematical Biology

, Volume 58, Issue 1, pp 43–63 | Cite as

Extending the quasi-steady state approximation by changing variables

  • José A. M. Borghans
  • Rob J. de Boer
  • Lee A. Segel
Article

Abstract

The parameter domain for which the quasi-steady state assumption is valid can be considerably extended merely by a simple change of variable. This is demonstrated for a variety of biologically significant examples taken from enzyme kinetics, immunology and ecology.

Keywords

Parameter Domain Slow Time Scale Fast Time Scale Replication Model Total Substrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Society for Mathematical Biology 1996

Authors and Affiliations

  • José A. M. Borghans
    • 1
  • Rob J. de Boer
    • 1
  • Lee A. Segel
    • 2
  1. 1.Theoretical BiologyUtrecht UniversityUtrechtThe Netherlands
  2. 2.Dept. of Applied Mathematics and Computer ScienceThe Weizmann Institute of ScienceRehovotIsrael

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