Anticardiolipin antibodies dissociate from protein in thermal shock

  • D. N. Abakushin
  • E. I. Khlopovskaya
  • R. S. Budagov
  • A. M. Poverennyi
Microbiology and Immunology
  • 19 Downloads

Abstract

Anticardiolipin antibodies are revealed in rat serum by solid-phase immunoenzyme assay 3 h after thermal burn of 30% of the body surface. An increase in serum concentration of the antibody after thermal burn may be due to dissociation of the antibody-protein complex.

Key Words

masked antibodies cardiolipin thermal shock immunoenzyme assay 

References

  1. 1.
    A. M. Poverennyi, R. A. Belovolova, V. I. Kiseleva, and A. P. Shinkarkina,Byull. Eksp. Biol. Med.,111, No. 5, 538–539 (1991).Google Scholar
  2. 2.
    V. A. Saenko, A. M. Rott, and A. M. Poverennyi,Ibid.,107, No. 2, 217–219 (1989).CrossRefGoogle Scholar
  3. 3.
    H. M. Cheng,Autoimmunity,19, 127–133 (1994).PubMedCrossRefGoogle Scholar
  4. 4.
    E. N. Harris, J. K. Chan, R. A. Asherson,et al., Arch. Intern. Med.,146, 2153–2156 (1986).PubMedCrossRefGoogle Scholar
  5. 5.
    E. N. Harris and S. S. Pierangeli,J. Clin. Immunoassay,17, 1–10 (1994).Google Scholar
  6. 6.
    The Antiphospholipid Antibodies in Stroke Study (APASS) Group, Neurology,43, 2069–2073 (1993).Google Scholar

Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • D. N. Abakushin
    • 1
  • E. I. Khlopovskaya
    • 1
  • R. S. Budagov
    • 1
  • A. M. Poverennyi
    • 1
  1. 1.Department of Radiation Biochemistry, Laboratory for the Modeling of Radiation and Nonradiation Effects, Medical Radiology Research CenterRussian Academy of Medical SciencesObninsk

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