Effect of amiridin on the conditioning of rats in a radial maze

  • Yu. V. Burov
  • A. O. Borisova
  • T. N. Pobakidze
Pharmacology and Toxicology

Abstract

The effect of amiridin and of the reference preparations tacrine, picamilon, and piracetam on conditioning in a radial maze is studied in intact rats. Long-term memory was significantly improved by amiridin, tacrine, and picamilon. Short-term memory was enhanced only by picamilon.

Key Words

amiridin short- and long-term memory, radial maze 

References

  1. 1.
    E. E. Bukatina, I. V. Grigor'eva, and E. I. Sokol'chik,Zh. Nevropatol. Psikhiatr.,91, No. 9, 53–58 (1991).PubMedGoogle Scholar
  2. 2.
    Yu. V. Burov, A. N. Inozerntsev L. L. Pragina,et al., Byull. Eksp. Biol. Med.,115, No. 2, 155–157 (1993).CrossRefGoogle Scholar
  3. 3.
    Yu. V. Burov, T. N. Robakidze, and A. E. Voronin, ——Ibid.,113, No. 1, 43–45, (1992).Google Scholar
  4. 4.
    Yu. V. Burov, T. N. Robakidze, L. V. Kadysheva, and S. A. Sukhanova, ——Ibid.,111, No. 6, 612–614 (1991).Google Scholar
  5. 5.
    Yu. V. Burov, T. N. Robakidze, L. V. Kadysheva,et al., Ibid. Byull. Eksp. Biol. Med., pp. 614–617.Google Scholar
  6. 6.
    G. V. Kovalev,Nootropic Agents [in Russian], Volgograd (1990).Google Scholar
  7. 7.
    Yu. V. Burov,Biol. Psychiatry,29, No. 118, 4488 (1991).Google Scholar
  8. 8.
    Yu. V. Burov, T. N. Robakidze, A. E. Voronin,et al., Biogenic Amines,9, No. 4, 327–335 (1993).Google Scholar
  9. 9.
    R. Cacabelos, A. Nordberg, J. Caamano J.,et al., Drugs Today,30, No. 4, 295–337 (1994).Google Scholar
  10. 10.
    H. Hodges, A. M. Ribeiro, J. A. Gray, and R. M. Marchbanks,Pharmacol. Biochem. Behav.,36, 291–299 (1990).PubMedCrossRefGoogle Scholar
  11. 11.
    I. Izquierdo,TIPS,8, 325–327 (1987).Google Scholar
  12. 12.
    P. T. Mannisto, O. Kutepova, K. Leinonen,et al., Drug Dev. Res.,30, No. 4, 219–228 (1993).CrossRefGoogle Scholar
  13. 13.
    T. Nabeshima, S. Yoshida, and T. Kameyama,Eur. J. Pharmacol.,154, 263–269 (1988).PubMedCrossRefGoogle Scholar
  14. 14.
    T. Yamamoto, M. Ohno, I. Kitajima,et al., Physiol. Behav.,53, No. 1, 5–11 (1993).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • Yu. V. Burov
    • 1
  • A. O. Borisova
    • 1
  • T. N. Pobakidze
    • 1
  1. 1.All-Russian Center for the Safety of Bioactive CompoundsStarya KupavnaMoscow Region

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