Bulletin of Experimental Biology and Medicine

, Volume 126, Issue 2, pp 775–776 | Cite as

Blood hyperviscosity syndrome: Adequacy of experimental model in SHR rats

  • M. B. Plotnikov
  • O. I. Aliev
  • A. A. Koltunov
  • M. Yu. Maslov
General Pathology and Pathological Physiology
Received:

Abstract

In comparison with Wistar rats, SHR rats demonstrated significantly higher viscosity of the whole blood and plasma, fibrinogen content, and erythrocyte aggregation, but a lower erythrocyte deformability. The differences in hemorheological indices in SHR and Wistar rats correspond to the deviation of these indices in the blood hyperviscosity syndrome observed in hypertensive patients.

Key Words

arterial hypertension blood hyperviscosity syndrome SHR rats 
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Copyright information

© Kluwer Academic/Plenum Publishers 1999

Authors and Affiliations

  • M. B. Plotnikov
    • 1
  • O. I. Aliev
    • 1
  • A. A. Koltunov
    • 1
  • M. Yu. Maslov
    • 1
  1. 1.Sibenan Division of the Russian Academy of Medical SciencesInstitute of Pharmacology, Tomsk Research CenterRussian

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