Bulletin of Experimental Biology and Medicine

, Volume 121, Issue 2, pp 148–150

Effect of ozone on lipid peroxidation in rat hearts isolated against the background of clinical death

  • K. N. Kontorshchikova
  • T. I. Solov'eva
Biophysics and Biochemistry

DOI: 10.1007/BF02446621

Cite this article as:
Kontorshchikova, K.N. & Solov'eva, T.I. Bull Exp Biol Med (1996) 121: 148. doi:10.1007/BF02446621


Clinical death of outbred albino rats ensues after rapid blood loss due to a cut in the coronary coronary artery. Five minutes later, the isolated heart is perfused with ozonized Krebs-Henseleit solution. The activity of the antioxidant system in the heart is increased compared with that during routine oxygenation. The intensity of lipid peroxidation assessed by the intensity of chemiluminescence and the amount of lipid peroxidation products is significantly decreased during ozonization.

Key Words

ozone isolated heart clinical death lipid peroxidation 

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • K. N. Kontorshchikova
    • 1
  • T. I. Solov'eva
    • 1
  1. 1.Central Research LaboratoryNizhnii Novgorod Medical AcademyNizhnii NovgoroodUSSR

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