Bulletin of Experimental Biology and Medicine

, Volume 122, Issue 2, pp 862–864 | Cite as

Effect of ozone on the liver in experimental chronic hepatitis

  • K. N. Kontorshchikova
  • I. M. Solopaeva
  • S. P. Peretyagin
Experimental Methods for Clinical Practice


Short-term administration of ozonized physiological solution to rats with chronic toxic hepatitis reduces the content of total lipids in the liver tissue, activates antioxidant enzymes, normalizes the level of diene conjugates, and reliably increases adenosine nucleotides, the number of normal hepatocytes being increased 2.2-fold. The data suggest that ozone can be used as a stimulator of regeneration of the pathologically altered liver.

Key Words

experimental chronic hepatitis ozone regeneration 


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Copyright information

© Plenum Publishing Corporation 1997

Authors and Affiliations

  • K. N. Kontorshchikova
    • 1
  • I. M. Solopaeva
    • 1
  • S. P. Peretyagin
    • 1
  1. 1.Central Research LaboratoryMedical AcademyNizhny Novgorod

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