Bulletin of Experimental Biology and Medicine

, Volume 120, Issue 4, pp 989–993 | Cite as

Structural and functional organization of the pain sensitivity component of lingual mechanoreceptor structures

  • Z. V. Lyubimova
  • S. A. Subrakova
  • A. A. Nikitina
  • O. P. Zelenkova


Examination of the structural and functional organization of tactile receptor structures in the rat tongue shows that the filiform mechanosensory papillae occupying the anterior free surface of the tongue are innervated by adrenergic, cholinergic, and peptidergic fibers. The location and sources of histamine are identified. All these components are thought to be involved in organizing the pain sensitivity of mechanosensory lingual formations.

Key words

tongue histamine innervation mechanosensory papillae 


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  1. 1.
    Z. V. Lyubimova and A. I. Esakov,Byull. Eksp. Biol. Med.,86, No 12, 641–644 (1978).Google Scholar
  2. 2.
    Z. V. Lyubimova, A. A. Kurnosova, and A. I. Esakov,Byull. Eksp. Biol. Med.,95, No 6, 116–119 (1983).CrossRefGoogle Scholar
  3. 3.
    Z. V. Lyubimova, S. A. Subrakova, and A. A. Nikitina,Byull. Eksp. Biol. Med.,114, No 12, 563–565 (1992).Google Scholar
  4. 4.
    V. M. Khayutin, in:Interoceptors, Regulation of Physiological Functions, and Behavior [in Russian], Leningrad (1976), pp. 230–247.Google Scholar
  5. 5.
    P. U. Angeletty, R. Levi-Montalcini, and F. Caramia,Brain Res.,43, No 2, 515–525 (1972).CrossRefGoogle Scholar
  6. 6.
    S. M. Bond, F. Cervero, and D. S. McQueen,J. Physiol. (London),315, 15 (1982).Google Scholar
  7. 7.
    S. H. Buck and T. F. Bures,Pharmacol. Rev.,38, 179–226 (1986).PubMedGoogle Scholar
  8. 8.
    B. Falck and Ch. Owman,Acta. Univ. Lundensis,2, No 7, 1–23 (1965).Google Scholar
  9. 9.
    S. Giuffrida, G. Parenti, T. Catti,et al., Pharmacol. Res. Commun.,20, No 3, 243–244 (1988).Google Scholar
  10. 10.
    M. J. Karnovsky and L. Roots,J. Histochem. Cytochem.,12, 219–221 (1964).PubMedGoogle Scholar
  11. 11.
    L. Landblad, J. M. Lundberg, E. Brodin,et al., Acta Otolaryngol. (Stockholm),96, 485–493 (1983).Google Scholar
  12. 12.
    P. Montavon, K. Lindstrand, A. Luts,et al., Regul. Pept.,32, 141–150 (1991).PubMedCrossRefGoogle Scholar
  13. 13.
    J. I. Nagy,Trends Neurosci.,5, No 10, 362–365 (1982).CrossRefGoogle Scholar
  14. 14.
    J. I. Nagy, M. Goedert, S. P. Hunt,et al., Neuroscience,7, No 12, 3137–3151 (1982).PubMedCrossRefGoogle Scholar
  15. 15.
    T. Nishimoto, H. Ishikawa, S. Wakisaka,et al., Anat. Rec.,212, No 4, 430–436 (1985).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1996

Authors and Affiliations

  • Z. V. Lyubimova
    • 1
  • S. A. Subrakova
    • 1
  • A. A. Nikitina
    • 1
  • O. P. Zelenkova
    • 1
  1. 1.Department of Human and Animal Anatomy and PhysiologyMoscow State Pedagogical UniversityMoscowUSSR

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