Design of specific antagonists of the fibrinogen receptor
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Summary
The aim of this work was to elucidate, using molecular modeling, structural and electrostatic common parameters of several selective fibrinogen receptor antagonists. From this theoretical pattern, we are currently designing and synthesizing original non-peptidic and selective carbohydrate-based antagonists of the fibrinogen receptor.
Key words
Integrin αIIbβ3 Molecular modeling RGDPreview
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© Kluwer Academic Publishers 1997