Initial stage of vascular bed development in telencephalon of human embryo

  • D. E. Korzhevskii
  • V. A. Otellin
Morphology and Pathomorphology


It was found that intracerebral blood vessels in human embryo telencephalon first appear on the 7th week of prenatal development as capillaries with poorly differentiated walls and signs of functional immaturity. The formation of the basal capillary membrane consisting of laminin and type IV collagen starts immediately after the formation of primary capillary network.

Key words

human embryogenesis blood vessels encephalon electron microscopy 


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  1. 1.
    D. E. Korzhevskii,Morfologiya,110, No. 5, 20–22 (1996).Google Scholar
  2. 2.
    F. J. Barkalow, M. J. Goodman, and T. N. Mayadas,Microcirculation,3, No. 1, 19–28 (1996).PubMedCrossRefGoogle Scholar
  3. 3.
    M. Bertossi, D. Virgintino, M. Errede, and L. Roncali,Microvasc. Res.,58, No. 1, 49–61 (1999).PubMedCrossRefGoogle Scholar
  4. 4.
    R. Dermietzel and D. Krause,Int. Rev. Cytol.,127, 57–109 (1991).PubMedGoogle Scholar
  5. 5.
    U. Kniesel, W. Risau, and H. Wolburg,Brain Res. Dev. Brain. Res.,96, 1–2, 229–240 (1996).PubMedCrossRefGoogle Scholar
  6. 6.
    W. Risau and H. Wolburg,Trends Neurosci.,13, No. 5, 174–178 (1990).PubMedCrossRefGoogle Scholar
  7. 7.
    Y. Yoshida, M. Yamada, K. Wakabayashi, and F. Ikuta,Brain Res. Dev. Brain Res.,44, No. 2, 211–219 (1988).PubMedCrossRefGoogle Scholar

Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • D. E. Korzhevskii
    • 1
  • V. A. Otellin
    • 1
  1. 1.Department of Morphology, Institute of Experimental MedicineRussian Academy of Medical SciencesSt. Petersburg

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