Dimebon improves learning in animals with experimental Alzheimer's disease
- Cite this article as:
- Lermontova, N.N., Lukoyanov, N.V., Serkova, T.P. et al. Bull Exp Biol Med (2000) 129: 544. doi:10.1007/BF02434871
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Systemic administration of antihistamine drug dimebon improves active avoidance conditioning in rats with chronic partial deprivation of cerebral cholinergic functions caused by intracerebroventricular injections of AF64A. The effects of dimebon on learning are similar to those of tacrine used in the treatment of Alzheimer's disease.