Bulletin of Experimental Biology and Medicine

, Volume 129, Issue 2, pp 131–133 | Cite as

Effect of parlodel on brain electrical activity in experimental depressive syndrome in rats

  • T. E. Iordanskaya
  • N. A. Krupina
  • G. N. Kryzhanovskii
  • I. N. Orlova
General Pathology and Pathological Physiology


In rats with experimental MPTP-induced depressive syndrome, chronic administration of parlodel prevented epileptiform activity, an increase in δ-band and a decrease in α-band spectral powers in the caudate-putamen structures, and an increase in δ-band spectral power in the hippocampus.

Key Words

depressive syndrome parlodel brain electrical activity rats pathological system 


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Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • T. E. Iordanskaya
    • 1
  • N. A. Krupina
    • 1
  • G. N. Kryzhanovskii
    • 1
  • I. N. Orlova
    • 1
  1. 1.Laboratory of General Pathology of Nervous System, Institute of General Pathology and PathophysiologyRussian Academy of Medical SciencesMoscow

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