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AGE

, 18:19 | Cite as

The effect of hybrid dysgenesis on life span of Drosophila

  • Tülay Konaç
  • A. Nihat Bozcuk
  • Aykut Kence
Article

Abstract

The effect of P-M hybrid dysgenesis on life span was investigated by using three strains of D. melanogaster (Canton-S, Harwich-w and Malatya w.t.). F1 hybrids of dysgenic crosses developed on 29°C and lived as adults on 25°C produced unexpected white eye color in both sexes. In one type of cross, which has strong P element activity, it was found that hybrid dysgenesis affects longevity distinctly and shortens it, especially in the F1 produced at higher developmental temperature.

Keywords

Life Span Element Activity Hybrid Dysgenesis Developmental Temperature Dysgenic Cross 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Bregliano JC, Kidwell MG: Hybrid dysgenesis determinants. In: Mobile genetics elements. Shapiro JA (ed). New York, Academic Press, pp. 363–410, 1983.Google Scholar
  2. 2.
    Engels WR, Benz WK, Preston CR, Graham PL, Phillips RW, Robertson HM: Somatic effects of P element activity in Drosophila melanogaster: pupal lethality. Genetics 117:745–757, 1987.PubMedGoogle Scholar
  3. 3.
    Kidwell MG: Hybrid dysgenesis in Drosophila melanogaster: factors affecting chromosomal contamination in the P-M system. Genetics 104:317–341, 1983.PubMedGoogle Scholar
  4. 4.
    O’Hare K, Rubin RM: Structure of P transposable elements in D. melanogaster and their sites of insertion and excision. Cell 34:25–35, 1983.PubMedCrossRefGoogle Scholar
  5. 5.
    O’Hare K: The mechanism and control of P element transposition in Drosophila melanogaster. Trends Genet. 1:250–254, 1985.CrossRefGoogle Scholar
  6. 6.
    Bozcuk AN: Genetics of longevity in Drosophila: the specific and hybridized effects of rolled, sepia, ebony and eyeless autosomal mutants. Exp. Geront. 16(5):415–428, 1981.CrossRefGoogle Scholar
  7. 7.
    Murray V: Hypothesis: are transposons a cause of aging? Mutation Research 237:59–63, 1990.PubMedCrossRefGoogle Scholar
  8. 8.
    Shmookler Reis RJ, Lumpkin CK, McGill JR, Riabowal KT, Goldstein S: Extrachremosomal circular copies of an “Inter-Alu” unstable sequence in human DNA are amplified during in vitro and in vivo aging. Nature 301:394–398, 1983.PubMedCrossRefGoogle Scholar
  9. 9.
    Vijg J, Uitterlinden AG, Mullaart E, Lohman PHM, Knook DI: Processing of DNA damage during aging: induction of genetic alteration. In: Molecular Biology of Aging: Gene Stability and Gene Expression. Sohal RS (ed), New York, Raven Press, pp. 155–171, 1985.Google Scholar
  10. 10.
    Kidwell MG, Novy JB: Hybrid dysgenesis in Drosophila melanogaster: sterility resulting from gonadal dysgenesis in P-M system. Genetics 92:1127–1140, 1979.PubMedGoogle Scholar
  11. 11.
    Kidwell MG, Kidwell JF, Sved JA: Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant treats including mutation, sterility and male recombinations. Genetics 86(4):813–833, 1977.PubMedGoogle Scholar
  12. 12.
    Finnegan DJ, Fawcett DH: Transposable elements in Drosophila melanogaster. Oxford Surveys on Eukaryotic Genes 3:1–62, 1986.PubMedGoogle Scholar
  13. 13.
    Getz C, Van Schaik C: somatic mutation in the wings of Drosophila melanogaster females dysgenic due to P elements when reared at 29°C. Mut. Res. 248:18–194, 1991.Google Scholar
  14. 14.
    Bozcuk AN: The effects of some genotypes on the longevity of adult Drosophila. Exp. Geront. 13: 279–286, 1978.CrossRefGoogle Scholar
  15. 15.
    Driver CJI, McKechnie SW: Transposable elements as a factor in the aging of Drosophila melanogaster. Annals of the New York Academy of Sciences, Vol. 673:83–91, 1993.Google Scholar
  16. 16.
    Konaç T, Bozcuk AN: The effects of hybrid dysgenesis on the life span of D. melanogaster. Abstracts of International Congress of IABG, Ancona, Italy, p. 39, 1991.Google Scholar
  17. 17.
    Woodruff R: Mutation and evaluation, life span reduction by transposons and premeiotic clusters. Abstracts of the 38th meeting of the Genetics Society of Australia, Monash University, p. 52, 1991.Google Scholar
  18. 18.
    Kidwell MG: Hybrid dysgenesis in Drosophila melanogaster: the relationship between the P-M and I-R interactions. Genet. Res. 33:205–217, 1979.CrossRefGoogle Scholar
  19. 19.
    Konaç T, Bozcuk AN: Hibrit disgenezis lie ilişkili sterilitenin D. melanogaster de gö sterilmesi. Doğa-Tr. J. of Biology 14(1):32–41, 1990.Google Scholar

Copyright information

© American Aging Association, Inc. 1995

Authors and Affiliations

  • Tülay Konaç
    • 1
  • A. Nihat Bozcuk
    • 2
  • Aykut Kence
    • 3
  1. 1.Turkish Atomic Energy Authority SarayAnkaraTurkey
  2. 2.Department of Biology, Beytepe CampusHacettepe UniversityAnkaraTurkey
  3. 3.Department of BiologyMiddle East Technical UniversityAnkara

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