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Bulletin of Experimental Biology and Medicine

, Volume 128, Issue 5, pp 1106–1108 | Cite as

Effects of regulatory peptides on changes in the content of brain stem catecholamine in rats during hypoxia and hemorrhage

  • A. G. Platonov
  • E. N. Goncharenko
  • Ya. V. Krushinskaya
  • N. Yu. Kudryashova
  • N. A. Sokolova
Biophysics and Biochemistry
  • 19 Downloads

Abstract

Effects of regulatory peptides FMRFa, thyroliberin, and Semax (ACTH4–10 analogue) on changes in the content of biogenic amines in rat brain stem observed 1 and 20 min after termination of hypoxia and 5 min after bloodletting (hemorrhage) were studied. The content of norepinephrine decreased to 82% of the control level 20 min after hypobaric hypoxia, while preliminary administration of the peptide complex abolished this effect.

Key Words

hypobaric hypoxia hemorrhage biogenic amines brain stem 

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Copyright information

© Kluwer Academic/Plenum Publishers 2000

Authors and Affiliations

  • A. G. Platonov
    • 1
  • E. N. Goncharenko
    • 1
  • Ya. V. Krushinskaya
    • 1
  • N. Yu. Kudryashova
    • 1
  • N. A. Sokolova
    • 1
  1. 1.Department of Biophysics, Department of Human and Animal Physiology, Biological FacultyM. V. Lomonosov Moscow State UniversityMoscow

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