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Skin lipids in rats administered with melatonin

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Abstract

Effects of the pineal hormone melatonin on skin lipids in Wistar rats were studied by thinlayer chromatography. The reaction was shown to be delayed. Contents of total lipids and the majority of fractions increased over 24 h after administration of melatonin. Concentrations of triglycerides and phospholipids decreased, while the contents of cholesterol, cholesterol esters, and free fatty acids increased by the end of the second day. Our findings indicate that the blood and subcutaneous fat, as well as changed metabolic interrelations of skin lipids are involved in the skin response to increased melatonin concentration.

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Authors and Affiliations

  1. Department of Biochemistry and Biotechnology, Tver' State University, Russian Academy of Medical Sciences, Moscow

    G. A. Gribanov & N. V. Kostyuk

  2. VILAR Research and Educational Center of Biomedical Technologies, Russian Academy of Medical Sciences, Moscow

    Yu. V. Abramov, L. B. Rebrov, V. A. Bykov & T. V. Volodina

  3. P. K. Anokhin Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow

    S. S. Pertsov

Authors
  1. G. A. Gribanov
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  2. N. V. Kostyuk
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  3. Yu. V. Abramov
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  4. L. B. Rebrov
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  5. V. A. Bykov
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  6. T. V. Volodina
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  7. S. S. Pertsov
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 4, pp. 463–465, April, 1999

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Gribanov, G.A., Kostyuk, N.V., Abramov, Y.V. et al. Skin lipids in rats administered with melatonin. Bull Exp Biol Med 127, 420–422 (1999). https://doi.org/10.1007/BF02433398

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  • DOI: https://doi.org/10.1007/BF02433398

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