Conjugal amyotrophic lateral sclerosis: a report on a couple from Sardinia, Italy

  • M. G. Rachele
  • V. Mascia
  • P. Tacconi
  • N. Dessi
  • F. Marrosu
  • M. Giagheddu
Case Report


A conjugal case of amyotrophic lateral sclerosis (ALS) observed in Sardinia, Italy is reported. This is believed to be the ninth such observation described in the literature. The couple had lived together for 38 years in a house adjacent to the distillery they owned. No exogenous factors were revealed which could explain the genesis of the disease in either patients. Particularly, exposure to alcohol does not appear to have been involved in causing ALS. On the basis of statistical and epidemiological evaluations, the most likely explanation is that this association was purely coincidental.

Key words

Amyotrophic lateral sclerosis Motor neuron diseases Epidemiology Degenerative diseases Conjugal diseases 


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Copyright information

© Springer-Verlag 1998

Authors and Affiliations

  • M. G. Rachele
    • 1
  • V. Mascia
    • 1
  • P. Tacconi
    • 1
  • N. Dessi
    • 2
  • F. Marrosu
    • 1
  • M. Giagheddu
    • 1
  1. 1.Institute of NeurologyUniversity of CagliariCagliariItaly
  2. 2.Computer CenterUniversity of CagliariCagliariItaly

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