Infantile autism and Duchenne muscular dystrophy

  • Junko Komoto
  • Seigo Usui
  • Saburo Otsuki
  • Akira Terao


We report a boy with autism and Duchenne muscular dystrophy. Myopathy was noted after 2 years of age and has since progressed slowly. At present this autistic child, 11 years 4 months old, has shown no signs of deterioration.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. American Psychiatric Association (1980).Diagnostic and statistical manual of mental disorders, (3rd ed.). Washington, D.C.: Author.Google Scholar
  2. Chess, S., (1971). Autism in children with congenital rubella.Journal of Autism and Childhood Schizophrenia, 1, 34–47.Google Scholar
  3. Chess, S. (1977). Follow-up report on autism in congenital rubella.Journal of Autism and Childhood Schizophrenia, 7, 69–81.CrossRefPubMedGoogle Scholar
  4. Coleman, M., (1979). Studies of the autistic syndromes. In R. Katzman (Ed.),Congenital and acquired cognitive disorders. Research Publications, Association for Research in Nervous and Mental Disease, 57, 265–275.Google Scholar
  5. Dubowitz, V. (1977) Mental retardation in Duchenne muscular dystrophy. In L. P. Rowland (Ed.),Pathogenesis of human muscular dystrophies (Excerpta Medica, ICS 404, p. 688). Amsterdam: Excerpta Medica.Google Scholar
  6. Duchenne de Boulogne GBA (1868). Recherches sur la paralysie musculaire pseudohypertrophique ou paralysie myosclerosique.Archives de Médicine Génétique, 11, 5–25.Google Scholar
  7. Folstein, S., & Rutter, M. (1977). Infantile autism; a genetic study of 21 twin pairs.Journal of Child Psychology and Psychiatry, 18, 297–321.PubMedGoogle Scholar
  8. Friedman, E. (1969). The “autistic syndrome” and phenylketonuria.Schizophrenia, 1, 249–261.Google Scholar
  9. Hackney, I. M. (1967). Autistic behavior patterns in phenylketonuric children.Canadian Psychiatric Association Journal, 12, 333–334.PubMedGoogle Scholar
  10. Hauser, S. L., DeLong, G. R., & Rosman, N. P. (1975). Pneumographic findings in the infantile autism syndrome; A correlation with temporal lobe disease.Brain, 98, 667–688.PubMedGoogle Scholar
  11. Leibowitz, D., & Dubowitz, V. (1981). Intellect and behavior in Duchenne muscular dystrophy.Developmental Medicine and Child Neurology, 23, 577–590.PubMedCrossRefGoogle Scholar
  12. Morrow, R. S., & Cohen, J., (1954). The psycho-social factors in muscular dystrophy.Journal of Child Psychiatry, 3, 70–80.PubMedGoogle Scholar
  13. Pratt, R. (1967).The genesis of neurological disorders. London: Oxford University Press.Google Scholar
  14. Rosenberger, P. B., & Nigam, M. P. (1979, September 13–15).Experimental phenylalaninemia and learning rate. Paper presented at the meeting of the Child Neurology Society, Dartmouth College, New Hampshire.Google Scholar
  15. Rosman, N. P. (1970). The cerebral defect and myopathy in Duchenne muscular dystrophy.Neurology, 20, 329–335.PubMedCrossRefGoogle Scholar
  16. Rutter, M. (1978). Diagnosis and definition of childhood autism.Journal of Autism and Childhood Schizophrenia, 8, 139–161.CrossRefPubMedGoogle Scholar
  17. Takaoka, Y., & Hazama, R. (1980). Review of therapeutic trial for patients with progressive muscular dystrophy.Saishin Igaku, 35, 999–1007. (In Japanese)Google Scholar
  18. Wakabayashi, S. (1979). A case of infantile autism associated with Down's syndrome.Journal of Autism and Developmental Disorders, 9, 31–36.CrossRefPubMedGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • Junko Komoto
    • 1
  • Seigo Usui
    • 1
  • Saburo Otsuki
    • 1
  • Akira Terao
    • 2
  1. 1.Misasa Branch HospitalOkayama University HospitalMisasa, TottoriJapan
  2. 2.Kawasaki Medical CollegeJapan

Personalised recommendations