Journal of Autism and Developmental Disorders

, Volume 14, Issue 2, pp 183–189

Autism and congenital cytomegalovirus

  • E. Gene Stubbs
  • Elizabeth Ash
  • Christopher P. S. Williams
Article

Abstract

Two cases of congenital cytomegalovirus infection associated with autism are reported. The viral hypothesis of autism is discussed along with a brief review of the literature. Suggestions are made for future research.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Chess, S. (1971). Autism in children with congential rubella.Journal of Autism and Childhood Schizophrenia, 1, 33–47.CrossRefPubMedGoogle Scholar
  2. DeLong, G. R., Bean, C. S., & Brown, F. R., III. (1981). Acquired reversible autistic syndrome in acute encephalopathic illness in children.Archives of Neurology, 38, 191–194.PubMedGoogle Scholar
  3. DeMyer, M. K., Barton, S., Alpern, G. D., Kimberlin, C., Allen, J., Yang, E., & Steele, R. (1974). The measured intelligence of autistic children.Journal of Autism and Childhood Schizophrenia, 4, 42–60.CrossRefPubMedGoogle Scholar
  4. Desmond, M. M., Wilson, G. S., Verniaud, W. M., Melnick, J. L., & Rawls, W. E. (1970). The early growth and development of infants with congenital rubella.Advances in Teratology, 4, 39–63.Google Scholar
  5. Folstein, S., & Rutter, M. (1977). Infantile autism: A genetic study of 21 twin pairs.Journal of Child Psychology and Psychiatry, 18, 297–321.PubMedGoogle Scholar
  6. Knobloch, H., & Pasamanick, B. (1974). Autistic, psychotic and other disturbed behavior. In H. Knobloch & B. Pasamanick (Eds.),Gesell and Amatruda's developmental diagnosis (3rd ed., pp. 320–339). New York: Harper & Row.Google Scholar
  7. Lotter, V. (1967). Epidemiology of autistic conditions in young children II. Some characteristics of the parents and children.Social Psychiatry, 1, 163–173.CrossRefGoogle Scholar
  8. Peterson, M. R., & Torrey, E. F. (1976). Viruses and other infectious agents as behavioral teratogens. In M. Coleman (Ed.),The autistic syndromes (pp. 23–42). New York: American Elsevier.Google Scholar
  9. Reynolds, D. W., Stagno, S., Stubbs, K. G., Dahle, A. J., Livingston, M. M., Saxon, S. S., & Alford, C. A. (1974). Inapparent congenital cytomegalovirus infection with elevated cord IgM levels.New England Journal of Medicine, 290, 291–296.PubMedCrossRefGoogle Scholar
  10. Rutter, M., & Lockyer, L. (1967). A five to fifteen year follow-up study of infantile psychosis I. Description of sample.British Journal of Psychiatry, 113, 1169–1182.PubMedCrossRefGoogle Scholar
  11. Shafritz, D. A., Shouval, D., Sherman, H. I., Hadziyannis, S. J., & Kew, M. C. (1981). Integration of hepatitis B virus DNA into genome of liver cells in chronic liver disease and hepatocellular carcinoma.New England Journal of Medicine, 305, 1067–1073.PubMedCrossRefGoogle Scholar
  12. Stubbs, E. G. (1978). Autistic symptoms in child with congenital cytomegalovirus infection.Journal of Autism and Childhood Schizophrenia, 8, 37–43.CrossRefPubMedGoogle Scholar
  13. Williams, R. S., Hauser, S. L., Purpura, D. P., DeLong, R., & Swisher, C. (1980). Autism and mental retardation: Neuropathologic studies performed in 4 retarded persons with autistic behavior.Archives of Neurology, 37, 749–753.PubMedGoogle Scholar
  14. Young, J. G., Caparulo, B. K., Shaywitz, B. A., Johnson, W. T., & Cohen, D. J. (1977). Childhood autism: Cerebrospinal fluid examination and immunoglobulin levels.Journal of Child Psychiatry, 16, 174–179.CrossRefGoogle Scholar

Copyright information

© Plenum Publishing Corporation 1984

Authors and Affiliations

  • E. Gene Stubbs
    • 1
  • Elizabeth Ash
    • 1
  • Christopher P. S. Williams
    • 1
  1. 1.School of Medicine, Crippled Children's DivisionThe Oregon Health Sciences UniversityPortland

Personalised recommendations