Biochemical Genetics

, Volume 30, Issue 3–4, pp 113–121

Glucose-6-phosphate dehydrogenase deficiency and sulfadimidin acetylation phenotypes in Egyptian oases

  • Laila Hussein
  • Gamal Yamamah
  • Adly Saleh


Screening of 1315 males from two Egyptian oases for glucose-6-phosphate dehydrogenase deficiency (G-6PD) found an incidence of 5.9%. The rate of acetylation of sulfadimidin was also studied, and a bimodal distribution was found with 73% rapid acetylators. There is a correlation between high frequency of G-6PD deficiency and high frequency of slow acetylation rate.

Key words

population study glucose-6-phosphate dehydrogenase deficiency drug acetylation polymorphism Egyptian oasis 


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Copyright information

© Plenum Publishing Corporation 1992

Authors and Affiliations

  • Laila Hussein
    • 1
  • Gamal Yamamah
    • 1
  • Adly Saleh
    • 1
  1. 1.Nutrition LaboratoryNational Research CentreGizaEgypt

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