Pediatric Radiology

, Volume 18, Issue 3, pp 232–234 | Cite as

Pulmonary aspergillosis appearing as chronic nodular disease in chronic granulomatous disease

  • M. J. Chusid
  • J. R. Sty
  • R. G. Wells
Short Reports

Abstract

Chronic nodular pneumonia is unusual in children. Three children are described who presented with diffuse nodular pulmonary disease and in whom lung biopsy demonstratedAspergillus infection. One child was known to have chronic granulomatous disease of childhood (CGD) and further investigation demonstrated CGD in the other two patients as well. These cases indicate thatAspergillus infection and CGD should be considered in the differential diagnosis in children who present with chronic diffuse nodular pneumonia.

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References

  1. 1.
    Fraser RG, Pare JAP (1976) Diagnosis of diseases of the chest, vol 4. WB Saunders, Philadelphia, p 81Google Scholar
  2. 2.
    Gallin JI, Buescher ES, Seligmann BE, Nath J, Gaither T, Katz P (1983) Recent advances in chronic granulomatous disease. Ann Intern Med 99: 657PubMedGoogle Scholar
  3. 3.
    Tauber AI, Borregaard N, Simons E, Wright J (1983) Chronic granulomatous disease: a syndrome of phagocyte oxidase deficiencies. Medicine 62: 286PubMedGoogle Scholar
  4. 4.
    Lazarus GM, Neu HC (1975) Agents responsible for infection in chronic granulomatous disease of childhood. J Pediatr 86: 415PubMedGoogle Scholar
  5. 5.
    Roback SA, Weintraub WH, Good RA, et al. (1971) Chronic granulomatous disease of childhood: surgical considerations. J Pediatr Surg 6: 601CrossRefPubMedGoogle Scholar
  6. 6.
    Chusid MJ, Gelfand JA, Nutter C, Fauci AS (1975) Pulmonary aspergillosis, inhalation of contaminated marijuana smoke, chronic granulomatous disease. Ann Intern Med 82: 682PubMedGoogle Scholar
  7. 7.
    Corrado ML, Cleri D, Fikrig SM, Phillips JC, Ahonkhai VI (1980) Aspergillosis in chronic granulomatous disease: therapeutic considerations. Am J Dis Child 134: 1092PubMedGoogle Scholar
  8. 8.
    Schoumacher RA, Tiller RE, Berkow RL (1987) Invasive pulmonary aspergillosis in an infant: an unusual presentation of chronic granulomatous disease. Pediatr Infect Dis 6: 215Google Scholar
  9. 9.
    Gaisie G, Bowen AD, Quattromani FL, Oh KS (1981) Chest wall invasion by aspergillus in chronic granulomatous disease of childhood. Pediatr Radiol 11: 203CrossRefPubMedGoogle Scholar
  10. 10.
    Rohatgi PK, Rohatgi NB (1984) Clinical spectrum of pulmonary aspergillosis. South Med J 77: 1291PubMedGoogle Scholar

Copyright information

© Springer-Verlag 1988

Authors and Affiliations

  • M. J. Chusid
    • 1
  • J. R. Sty
    • 2
  • R. G. Wells
    • 2
  1. 1.Department of PediatricsChildren's Hospital of Wisconsin and The Medical College of WisconsinMilwaukeeUSA
  2. 2.Department of RadiologyChildren's Hospital of Wisconsin and The Medical College of WisconsinMilwaukeeUSA

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