Archives of Gynecology and Obstetrics

, Volume 255, Supplement 2, pp S259–S271 | Cite as

Transplantation hépatique et grossesse: Perspectives en 1994

  • Ph. Sauthier
  • P. Hohlfeld
  • F. Mosimann
  • H. Bossart
1. Hauptthema/Premier Thème Principal Lebererkrankungen In Der Schwangerschaft Pathologie Hépatique Et Grossesse
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Résumé

Les auteurs rapportent le cas d'une grossesse chez une patiente IIIG IP de 24 ans ayant subi 2 ans auparavant une transplantation hépatique pour échinococccose alvéolaire. La grossesse et l'accouchement se sont déroulés sans problème obstétrical ni hépatique. La grossesse semble peu influencer la transplantation hépatique et les rejets sont rares. Les principales complications maternelles sont l'hypertension artérielle, la gestose, l'anémie et l'hyperbilirubinémie. Les complications foetales sont principalement la prématurité et le retard de croissance intrautérin. Le mode d'accouchement dépend des complications obstétricales rencontrées. L'utilisation de ciclosporine ne présente pas de problème, mais reste discutée durant l'allaitement. La grossesse après transplantation hépatique est possible dans un délai de 9–12 mois, mais nécessite une surveillance multidisciplinaire stricte. Toute patiente transplantée en âge de procréer et qui ne désire pas de grossesse nécessite une contraception et la préférence sera accordée aux méthodes barrières.

Summary

The authors report a caseof pregnancy in a 24-year-old, gravida-3, para-1 patient who had previously undergone liver transplantation for alveolar echinococcosis. Pregnancy and delivery were uneventful with no obstetrical or liver complications. Pregnancy seems to have little effect on liver transplants and rejection is seldom observed. Primary maternal complications are hypertension, preeclampsia, anemia and hyperbilirubinemia. Primary fetal complications include premature delivery and growth retardation. The mode of delivery depends on the obstetrical situation. Cyclosporin may be used during pregnancy. The risk of breastfeeding has not been clearly established. Pregnancy after liver transplantation is possible after 9 to 12 months but requires strict multidisciplinary surveillance. Barrier methods remain the preferred method of contraception for liver transplant patients.

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Copyright information

© Springer-Verlag 1994

Authors and Affiliations

  • Ph. Sauthier
    • 1
  • P. Hohlfeld
    • 1
  • F. Mosimann
    • 2
  • H. Bossart
    • 1
  1. 1.Département de Gynécologie-ObstétriqueCHUVLausanneSchwitzerland
  2. 2.Département de ChirurgieCHUVLausanneSchwitzerland

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