Pediatric Radiology

, Volume 19, Issue 2, pp 91–93 | Cite as

Magnetic resonance imaging of the brain in congenital cytomegalovirus infection

  • Ch. Boesch
  • J. Issakainen
  • G. Kewitz
  • R. Kikinis
  • E. Martin
  • E. Boltshauser
Selected Papers From The ESPR Meeting In Montreux, Switzerland, 13–16 April 1988


Ten children (age 2 months to 8 years) with a congenital cytomegalovirus (CMV) infection were studied by magnetic resonance imaging (MRI) using a 2.35 Tesla magnet. CMV infection was confirmed by serological investigations and virus culture in the neonatal period. Nine children had severe mental retardation and cerebral palsy, 1 patient suffered from microcephaly, ataxia and deafness. The cranial MRI examination showed the following abnormalities (N): dilated lateral ventricles (10) and subarachnoid space (8), oligo/pachygyria (8), delayed/pathological myelination (7), paraventricular cysts (6), intracerebral calcification (1). This lack of sensitivity for calcification is explainable by the basic principles of MRI. The paraventricular cystic lesions were adjacent to the occipital horns of the lateral ventricles and separated only by a thin membrane. This finding might represent a “new sign” for congenital CMV infection in MRI examinations, being characteristic but nevertheless nonspecific, like calcification in CT.


Magnetic Resonance Imaging Cerebral Palsy Lateral Ventricle Cystic Lesion Subarachnoid Space 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag 1989

Authors and Affiliations

  • Ch. Boesch
    • 1
  • J. Issakainen
    • 1
  • G. Kewitz
    • 1
  • R. Kikinis
    • 1
  • E. Martin
    • 1
  • E. Boltshauser
    • 1
  1. 1.Departments of Magnetic Resonance and NeurologyUniversity Children's HospitalZurichSwitzerland

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