Effect of disuse on the ultrastructure of the achilles tendon in rats
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We examined the influence exerted, through disuse of the hindlimb, on the collagen fibres of the achilles tendon in rats. With disuse the body mass decreased by 28%, and the mass of soleus muscle decreased by 20%. A decrease in the surface area and diameter was observed in the experimental group when compared to the control group. A histogram of the collagen fibres showed a decrease of the thick fibres in the experimental group. The maximum surface area of collagen fibres in the experimental group was seen to be only 43% of that of the control group. These results showed a decrease in the thickness of the collagen fibres of the achilles tendon through disuse. This seemed to suggest that resistance to tension is decreased by disuse.
Key wordsCollagen fibre Achilles tendon Disuse Atrophy Ultrastructure
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- Laros GS, Tipton CM, Cooper RR (1971) Influence of physical activity on ligament insertions in the knee of dogs. J Bone Joint Surgy [Am] 53:275–286Google Scholar
- Morey ER (1979) Spaceflight and bone turnover: correlation with a new rat model of weightlessness. BioScience 29:168–172Google Scholar
- Nakagawa Y, Sato T, Fukuda Y, Hirota K (1988) Effect of aerobic and anaerobic training on collagen fiber of tendon in rats. Jpn J Phys Fitness Sports Med 37:100–108Google Scholar
- Noyes FR, Torvic PJ, Hyde WB, Delucas JL (1974) Biomechanics of ligament failure. J Bone Joint Surg [Am] 56A:1406–1418Google Scholar
- Steffen JM, Deavers DR, Musacchia XJ (1980) Increased excretion of water, urea, Na+ and K− during head-down-tilt hypokinesia: a question of diet or antiorthostrasis. Physiologist 23:84Google Scholar