Primates

, Volume 23, Issue 3, pp 444–452

Temporal relationship of hormonal peaks to ovulation and sex skin deturgescence in the baboon

  • Abubakar A. Shaikh
  • Shamim A. Shaikh
  • Cornelio L. Celaya
  • Ignacio Gomez
Article

Abstract

The purpose of this study was to determine the temporal relationship of peak levels of oestradiol (E2), LH and progesterone to ovulation and sex skin deturgescence in the baboon. A total of 55 baboons were used in these studies. Hormonal levels were measured in 47 cycles and ovulation was documented by laparoscopic examination in 26 of these cycles. A temporal relationship of ovulation to sex skin deturgescence was established in 57 cycles. The mean interval from E2 peak to ovulation was 41.4±2.3 hr, the interval from E2 peak to LH peak was 17.3±2.0 hr and that from LH peak to ovulation was 18.4±2.0 hr. Eleven baboons showed an LH peak on the day of the E2 peak. The number of days to the first sign of sex skin deturgescence after ovulation was 2.07±0.14 days (range 0–5 days). Nineteen cycles (33.3%) showed sex skin deturgescence 1 day after ovulation, another 19 cycles (33.3%) showed sex skin deturgescence 2 days after ovulation, and only 13 cycles (22.8%) showed sex skin deturgescence 3 days after ovulation. Sex skin deturgescence was observed on day 0, 4 or 5 postovulation in only two baboons.

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References

  1. Abraham, G. E., W. D. Odell, R. S. Swerdloff &K. Hopper, 1972. Simultaneous radioimmunoassay of plasma FSH, LH, progesterone, 17-hydroxyprogesterone and estradiol-17β during the menstrual cycle.J. Clin. Endocrinol. Metabl., 34: 312–318.Google Scholar
  2. Castracane, V. D., G. T. Moore &A. A. Shaikh, 1979. Ovarian function in hysterectomizedMacaca fascicularis.Biol. Reprod., 20: 462–472.CrossRefPubMedGoogle Scholar
  3. Clifton, D. K., R. A. Steiner &J. A. Resko, 1975. Estrogen-induced gonadotropin release in the ovariectomized rhesus monkey and its advancement by progesterone.Fed. Proc., 34: 288 (393).Google Scholar
  4. Ferin, M., A. Tempone, P. E. Zimmering &R. L. Vande Wiele, 1969. Effect of antibodies to 17β-estradiol and progesterone on the estrous cycle of the rat.Endocrinology, 85: 1070–1078.PubMedGoogle Scholar
  5. Gillman, J. &C. Gilbert, 1946. The reproductive cycle of the chacma baboon (Papio ursinus) with special reference to the problems of menstrual irregularities as assessed by the behavior of the sex skin.S. Afr. J. Med. Sci., 11: 1–30.Google Scholar
  6. Goncharov, N., T. Aso, Z. Cekan, N. Pachalia &E. Diczfalusy, 1976. Hormonal changes during the menstrual cycle of the baboon (Papio hamadryas).Acta Endocrinol., 82: 396–412.PubMedGoogle Scholar
  7. Goodman, A. L., C. D. Descalzi, D. K. Johnson &G. D. Hodgen, 1977. Composite pattern of circulating LH, FSH, estradiol and progesterone during the menstrual cycle in cynomolgus monkeys.Proc. Soc. Exp. Biol. Med., 155: 479–481.PubMedGoogle Scholar
  8. Greenwood, F. C., W. M. Hunter &J. S. Glover, 1963. The preparation of131I-labelled human growth hormone of high specific radioactivity.Biochem. J., 89: 114–123.PubMedGoogle Scholar
  9. Harrison, R. M. &W. R. Dukelow, 1974. Morphological changes in theSaimiri sciureus ovarian follicles as detected by laparoscopy.Primates, 15: 305–309.CrossRefGoogle Scholar
  10. Hartman, C. G., 1962. The premenstrual (Postovulatory) phase: how variable? In:Science and the Safe Period,C. G Hartman (ed.), Williams & Wilkins, Baltimore, pp. 226–234.Google Scholar
  11. Hendrickx, A. G. &D. C. Kraemer, 1969. Observations on the menstrual cycle, optimal mating time and pre-implanation embryos of the baboon,Papio anubis andPapio cynocephalus.J. Reprod. Fert., Suppl., 6: 119–128.Google Scholar
  12. Hotchkiss, J., L. E. Atkinson &E. Knobil, 1971. Time course of serum oestrogen and luteinizing hormone (LH) concentrations during the menstrual cycle of the rhesus monkey.Endocrinology, 89: 177–183.PubMedGoogle Scholar
  13. Jewett, D. A. &W. R. Dukelow, 1972. Serial observations of follicular morphology near ovulation inMacaca fascicularis.J. Reprod. Fert., 31: 287–290.Google Scholar
  14. Karsch, F. J., D. J. Dierschke, R. F. Weick, T. Yamaji, J. Hotchkiss &E. Knobil, 1973. Positive and negative feedback control by estrogen of luteinizing hormone secretion in the rhesus monkey.Endocrinology, 92: 799–804.PubMedGoogle Scholar
  15. ————,R. F. Weick, W. R. Butler, D. J. Kierschke, L. C. Krey, G. Weiss, J. Hotchkiss, T. Yamaji &E. Knobil, 1973. Induced LH surges in the rhesus monkey: Strength-duration characteristics of the estrogen stimulus.Endocrinology, 92: 1740–1747.PubMedGoogle Scholar
  16. Koyama, T., A. de la Pena &N. Hagino, 1977. Plasma estrogen, progestin and luteinizing hormone during the normal menstrual cycle in the baboon: Role of luteinizing hormone.Amer. J. Obstet. Gynecol., 127: 67–72.Google Scholar
  17. Labhsetwar, A. P., 1970. Role of estrogens in ovulation: A study using the estrogen-antagonist, I.C.E. 46,474.Endocrinology, 87: 542–551.PubMedGoogle Scholar
  18. Maples, W. R., 1968. Classification of the Kenya baboon. Ph. D. Dissertation, Univ. of Texas, Austin, Texas.Google Scholar
  19. McDonald, P. G. &D. P. Gilmore, 1971. The effect of ovarian steroids on hypothalamic thresholds for ovulation in the female rat.J. Endocrinol., 49: 421–429.PubMedGoogle Scholar
  20. Nigi, H., 1977. Laparoscopic observations of ovaries before and after ovulation in the Japanese monkey (Macaca fuscata).Primates, 18: 243–259.Google Scholar
  21. Nillius, S. J. &L. Wide, 1971. Induction of a midcycle-like peak of luteinizing hormone in young women by exogenous oestradiol-17β.J. Obstet. Gynaecol. Br. Commonwlth., 78: 822–827.Google Scholar
  22. Pauerstein, C. J., C. A. Eddy, H. D. Croxatto, R. Hess, T. M. Siler-Khodr &H. B. Croxatto, 1978. Temporal relationships of estrogen, progesterone and luteinizing hormone levels to ovulation in women and infrahuman primates.Amer. J. Obstet. Gynecol., 130: 876–886.Google Scholar
  23. Resko, J. A., M. J. Koering, R. W. Goy &C. H. Phoenix, 1975. Preovulatory progestins: Observations on their source in rhesus monkeys.J. Clin. Endocrinol. Metab., 41: 120–125.PubMedGoogle Scholar
  24. Ross, G. T., 1976. Preovulatory determinants of human corpus luteum function.Eur. J. Obstet. Gynecol. Reprod. Biol., 6: 147–155.CrossRefPubMedGoogle Scholar
  25. Saksena, S. K. &A. A. Shaikh, 1974. Effect of intrauterine devices on preovulatory LH and progesterone levels in the cyclic hamster.J. Reprod. Fertil., 38: 205–210.PubMedGoogle Scholar
  26. Shaikh, A. A., R. H. Naqvi &S. A. Shaikh, 1978. Concentrations of oestradiol-17β and progesterone in the peripheral plasma of the cynomolgus monkey (Macaca fascicularis) in relation to the length of the menstrual cycle and its component phases.J. Endocrinol., 79: 1–7.PubMedGoogle Scholar
  27. Sherman, B. M. &S. G. Korenman, 1974. Measurement of plasma LH, FSH, oestradiol and progesterone in disorders of the human menstrual cycle: the short luteal phase.J. Clin. Endocrinol. Metab., 38: 89–93.PubMedGoogle Scholar
  28. Shirley, B., J. Wolinsky &N. B. Schwartz, 1968. Effects of a single injection of an estrogen antagonist on the estrous cycle of the rat.Endocrinology, 82: 959–968.PubMedGoogle Scholar
  29. Strott, C. A., C. M. Cargille, G. T. Ross &M. B. Lipsett, 1970. The short luteal phase.J. Clin. Endocrinol. Metab., 30: 246–251.PubMedGoogle Scholar
  30. Vande Wiele, R. L., J. Bogumil, I. Dyrenfurth, M. Ferin, R. Jewelewicz, M. Warren, T. Rizkallah &G. Mikhail, 1970. Mechanisms regulating the menstrual cycle in women.Recent Prog. Horm. Res., 26: 63–103.Google Scholar
  31. Wildt, D. E., L. L. Doyle &R. M. Harrison, 1977. Correlation of perineal swelling with serum ovarian hormone levels, vaginal cytology and ovarian follicular development during the baboon reproductive cycle.Primates, 18: 261–270.Google Scholar
  32. Wu, C. H., L. E. Lundy &S. G. Lee, 1973. A rapid radioimmunoassay for plasma estrogen.Amer. J. Obstet. Gynecol., 115: 169–180.Google Scholar
  33. Yamaji, T., D. J. Kierschke, J. Hotchkiss, A. N. Bhattacharya, A. H. Surve &E. Knobil, 1971. Estrogen induction of LH release in the rhesus monkey.Endocrinology, 89: 1034–1041.PubMedGoogle Scholar
  34. Zuckerman, S., 1930. The menstrual cycle of primates. I. General nature and homology.Proc. Zool. Soc. Lond., 691.Google Scholar
  35. ----, 1937. The duration and phases of the menstrual cycle in primates.Proc. Zool. Soc. Lond., 315–325.Google Scholar
  36. ---- &A. S. Parkes, 1932. The menstrual cycle of the primates. V. The cycle of the baboon.Proc. Zool. Soc. Lond., 139–147.Google Scholar

Copyright information

© Japan Monkey Centre 1982

Authors and Affiliations

  • Abubakar A. Shaikh
    • 1
  • Shamim A. Shaikh
    • 1
  • Cornelio L. Celaya
    • 2
  • Ignacio Gomez
    • 2
  1. 1.Department of Veterinary Physiology and Pharmacology, College of Veterinary MedicineTexas A&M UniversityCollege StationU.S.A.
  2. 2.Southwest Foundation for Research and EducationSan AntonioU.S.A.

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